Heteropyxis natalensis (Heteropyxidaceae) is traditionally used to treat respiratory disorders, and as a decongestant and antimicrobial agent.
The seasonal variation of the hydrodistilled essential oil was investigated. Three trees in the Johannesburg Botanical Garden (Gauteng) indicated
similar chemical profiles with fluctuation in the levels of the two major constituents (1,8-cineole and limonene). Little variation between the
antimicrobial activity of seasonally collected samples was documented, with standard deviations of ±0.3 to ±3.3 depending on the pathogen
studied. Moderate antimicrobial activity (3.0–16.0 mg/ml) was noted for most pathogens tested with Cryptococcus neoformans exhibiting the
highest sensitivity (2.0–3.0 mg/ml). The chemogeographical variation of the oil composition from five of the seven distinct localities studied all
contains 1,8-cineole and limonene as major constituents. The antimicrobial study of these samples indicated little variability between localities
(standard deviation of ±0.5 to ±3.8). As observed in the seasonal variation study, C. neoformans displayed the highest sensitivity (0.5–2.0 mg/ml).
One oil sample (Lagalametse), was distinctly different both chemically and microbiologically.
| Identifer | oai:union.ndltd.org:netd.ac.za/oai:union.ndltd.org:tut/oai:encore.tut.ac.za:d1000828 |
| Date | 27 July 2007 |
| Creators | Van Vuuren, SF, Viljoen, AM, Őzek, T, Demirci, B, Başer, KHC |
| Publisher | Elsevier |
| Source Sets | South African National ETD Portal |
| Language | English |
| Detected Language | English |
| Type | Text |
| Format | |
| Rights | © 2007 SAAB. |
| Relation | South African Journal of Botany |
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