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Mobile phone radiation does not induce pro-apoptosis effects in human spermatozoa

Recent reports suggest that mobile phone radiation may
diminish male fertility. However, the effects of this radiation on
human spermatozoa are largely unknown. The present study
examined effects of the radiation on induction of apoptosisrelated
properties in human spermatozoa. Ejaculated, densitypurified,
highly motile human spermatozoa were exposed to
mobile phone radiation at specific absorption rates (SARs) of
2.0 and 5.7 W/kg. At various times after exposure, flow
cytometry was used to examine caspase 3 activity, externalization
of phosphatidylserine (PS), induction of DNA strand
breaks, and generation of reactive oxygen species. Mobile
phone radiation had no statistically significant effect on any of
the parameters studied. This suggests that the impairment of
fertility reported in some studies was not caused by the induction
of apoptosis in spermatozoa.

Identiferoai:union.ndltd.org:netd.ac.za/oai:union.ndltd.org:tut/oai:encore.tut.ac.za:d1001205
Date11 May 2010
CreatorsFalzone, N, Huyser, C, Franken, DR, Leszczynski, D
PublisherRadiation Research
Source SetsSouth African National ETD Portal
LanguageEnglish
Detected LanguageEnglish
TypeText
FormatPdf
Rightsc2010 Radiation Research Society.
RelationRadiation Research Society

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