M. Tech. / Fusarium species are common contaminants of maize and are also capable of producing mycotoxins, in particular the fumonisin. These are implicated in animal and human mycotoxins fumonisin B1 (FB1) for example, has been associated in the aetiology of oesophageal cancer in South Africa and other parts of the world, i.e., China and Iran. Because maize is the staple diet of the South African rural population, this study was designed with the aim of monitoring Fusarium spp. and FB1 in the food of rural people of Venda, Limpopo province of South Africa, during the course of processing maize into porridge which gave a means of estimating dietary exposure to this mycotoxin. Measurement of fumonisin in the excreta of these people allowed a determine of the extent to which FB1 the body is actually exposed to the mycotoxin.Fumonisin B1 has been identified as a major fungal contaminant on maize, especially in the home grown crops intended for human consumption. Thus the rural population of Limpopo Province is at high risk from FB1 exposure and it is therefore of importance to assess this exposure by the analysis of suitable samples.It can be seen that levels of FB1 in maize from Venda are quite high, as several of these samples had exceeded levels above 1750 μg/kg as recommended as maximum tolerance levels by theEuropean Commission. It is equally seen that a much higher proportion of this mycotoxin was destroyed by processing maize to porridge. And because porridge and other maize-based products are usually consumed on a daily basis, the low levels found in the present study must not be under-estimated, as such levels may accumulate over time and cause more severe chronic effects in humans. When setting daily tolerable levels of FB1 in foods in South Africa, it is imperative to take into account the food habits, especially those within the rural communities
| Identifer | oai:union.ndltd.org:netd.ac.za/oai:union.ndltd.org:uj/uj:2358 |
| Date | 04 June 2012 |
| Creators | Phoku, Judith Zanele |
| Source Sets | South African National ETD Portal |
| Detected Language | English |
| Type | Thesis |
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