M.Tech. (Homoeopathy) / Cat allergy is an Immunoglobulin E (IgE) response by the body in hypersensitive individuals, triggered by exposure to cat allergen, which can be found in cat saliva and cat dander. Cat allergy produces a number of symptoms which negatively influence daily living and may be exacerbated in hypersensitive individuals to halt daily functioning. Conventional treatment for cat allergy comprises of antihistamines, anti-inflammatories, leukotrine blockers and decongestants, which have many adverse effects, are not always effective and may lead to drug tolerance. To date, research has been conducted by Naidoo et al., (2011) on the efficacy of the homoeopathic complex of Cat saliva 9cH and Histaminum 9cH in treating the symptoms of cat allergy, which yielded positive and statistically significant results according to the skin prick test. The desensitising effect of this complex on blood IgE levels has not yet been studied. The aim of this study was to determine the efficacy of Cat saliva 9cH and Histaminum 9cH in the desensitization of cat allergy, by use of cat specific RAST tests and a symptom score card. The complex of Cat saliva 9cH and Histaminum 9cH was prepared according to homoeopathic principles and prescribed according to isopathic principles. Thirty male and female participants between the ages of 18 and 45, who had a positive RAST test result for cat allergy, were selected for this four week, double-blind, placebo-controlled study. The RAST tests were performed at the beginning of the study (week 1) and at the end of the study (week 4). The participants were randomly divided into treatment and control groups. The treatment group received the homoeopathic complex of Cat saliva 9cH and Histaminum 9cH and the control group received the placebo. Participants were asked to take two tablets in the morning and two tablets at night sublingually for the duration of the study period. Each participant received a symptom score card which was to be completed at the end of each week. The symptom score card rated the severity, frequency and duration of their symptoms. The results were statistically analysed using, the Friedman-K Related Samples Test, the Wilcoxon Signed Ranks Test and the Mann-Whitney U Test. The results showed that the homoeopathic complex of Cat saliva 9cH and Histaminum 9cH did not improve the IgE levels or IgE grading in the treatment group. When looking at the symptoms, the treatment group had a statistically significant improvement in the severity, duration and frequency of the symptom “red itchy eyes”, as well as improved duration of the symptoms “runny itchy stuffy nose” and “sneezing”; while the control group was found to have a statistically significant improvement in the frequency of the symptom “red itchy eyes”, “scratchy throat”, as well as the duration of “red itchy eyes”. In conclusion it can be said that the homoeopathic complex of Cat saliva 9cH and Histaminum 9cH did not produce desensitization to cat allergen, thus leading to the rejection of the hypothesis and the acceptance of the null hypothesis.
| Identifer | oai:union.ndltd.org:netd.ac.za/oai:union.ndltd.org:uj/uj:7466 |
| Date | 18 April 2013 |
| Creators | Du Plessis, Erin |
| Source Sets | South African National ETD Portal |
| Detected Language | English |
| Type | Thesis |
| Rights | University of Johannesburg |
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