Introduction: The decision as to the most appropriate site of care of a patient with
community-acquired pneumonia (CAP), especially whether hospitalisation is
warranted or not, is one of the most important decisions in the overall emergency
department management of such patients. It has consequences both with regard to
the level of treatment received by the patient as well as the overall costs of
treatment. Several tools have been developed to predict mortality and/or determine
which patients could be sent home and treated safely with good clinical outcomes.
The CRB-65 score is one of the validated severity of illness scoring tools
recommended. This scoring system may be of particular benefit in resourceconstrained
areas, as it is easier to use.
Study’s aim: To determine whether it would be useful to introduce the CRB-65
severity of illness score in the routine evaluation of patients with CAP in the Helen
Joseph Hospital Emergency Department (HJH ED).
Study’s objectives: To determine what criteria HJH ED doctors use in their
decision to admit or discharge CAP patients; to determine the frequency with which
the CRB-65 severity of illness score is used in current practice by the HJH ED
doctors for admitting or discharging CAP patients; and to determine the potential
performance of the CRB-65 severity of illness score in the management of patients
with CAP in the HJH ED.
Design: Prospective, observational, hospital-based study.Patients and methods: All patients 18 years of age and older with the diagnosis
of CAP constituted our study population. Data from 152 patients seen between
February 2011 and April 2011 was collected and analysed. Outcome measures
included hospital admission or discharge, time to clinical stability, length of hospital
stay, and mortality.
Results: Overall, 152 patients (79 females and 73 males) were included in the
analysis. The median age was 36.5 years, with a range from 20 to 87 years. The
chest radiograph was the commonest criterion (41%) used by the HJH ED doctors to
determine the need for admission of the patients with CAP, while the haemodynamic
parameters were the commonest criteria used (25.9%) for discharge decisions. On
only three occasions was the CRB-65 score utilised out of the 193 criteria
documented (1.55%).
There was a significantly shorter time to clinical stability (p = 0.0069), but no
tendency to a shorter length of hospital stay in patients with a lower CRB-65 score (p
= 0.5694). Patients with a higher CRB-65 score were at significantly higher risk of
death compared to patients with a lower CRB-65 score (p < 0.001). There were no
deaths from outpatients, but there were a total of five deaths observed from the inhospital
patients of which 3/5 patients (60%) would potentially have been classified
as intermediate mortality risk and the remaining 2/5 patients (40%) as high mortality
risk if the CRB-65 score had been the only criterion used as the standard for site of
care decisions by the HJH ED doctors.
Conclusion: The chest radiograph was the commonest criterion used by the HJH
ED doctors to determine the need for admission of the patients with CAP, while the
haemodynamic parameters were the commonest criteria used for discharge decision. The CRB-65 score is not frequently being used in current practice by the
HJH ED doctors for admitting or discharging CAP patients.
This study demonstrates the ability of the CRB-65 severity of illness score to
accurately predict both the time to clinical stability for patients hospitalised with CAP
and the risk of death associated. In addition, this study documents that the CRB-65
severity of illness score performed well in its ability to determine the initial site of care
for patients with CAP.
Setting: Emergency Department of the Helen Joseph Hospital.
| Identifer | oai:union.ndltd.org:netd.ac.za/oai:union.ndltd.org:wits/oai:wiredspace.wits.ac.za:10539/11022 |
| Date | 17 January 2012 |
| Creators | Kabundji, Dalton Mulombe |
| Source Sets | South African National ETD Portal |
| Language | English |
| Detected Language | English |
| Type | Thesis |
| Format | application/pdf |
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