ABSTRACT
Aim
The aim of this study is to compare the degree of severity of chronic periodontitis in HIVseropositive
subjects with chronic periodontitis to control subjects with chronic periodontitis,
in the Ga-Rankuwa area in South Africa.
Methods
Two cohorts of subjects with chronic periodontitis were recruited for this study over a period
of time: thirty HIV-seropositive subjects; and 30 control subjects presumed to be HIV -
seronegative and apparently in good health.
Results
When all the periodontal indices were compared and evaluated there was no association
between HIV-serostatus and the periodontal indices. When periodontal indices were
compared between HIV-seropositive subjects using highly active anti-retroviral therapy
(HAART), and HAART-naïve subjects, there was no statistical differences regarding gingival
recession, plaque index and bleeding index. However, the mean pocket depth in HAARTnaïve
seropositive subjects was slightly greater than in HIV-seropositive subjects using
HAART. Correlation coefficient of mean pocket depth in relation to log CD4+ T cell count
in the HIV-seropositive HAART-naïve group of subjects showed a significant negative
correlation (P = -0.947), but there was no correlation between the mean gingival recession values and the log CD4+ T cell counts in the same group (P=0.303). For the HIVseropositive
subjects using HAART the correlation coefficient test failed to show significant
statistical relationships between log CD4+ T cell count and mean pocket depth (P=0.903) and
mean gingival recession (P=0.312) in HIV-seropositive subjects using HAART.
Conclusion
HIV-seropositive subjects with chronic periodontitis show clinical manifestations of similar
degree of their periodontal disease to those of healthy control subjects with chronic periodontitis, with no differences in the mean pocket depth, gingival recession, plaque index
and bleeding index.
| Identifer | oai:union.ndltd.org:netd.ac.za/oai:union.ndltd.org:wits/oai:wiredspace.wits.ac.za:10539/5744 |
| Date | 13 October 2008 |
| Creators | Khammissa, Razia Abdool Gafaar |
| Source Sets | South African National ETD Portal |
| Language | English |
| Detected Language | English |
| Type | Thesis |
| Format | application/pdf |
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