Charles University in Prague Faculty of pharmacy in Hradec Králové Department of Biological and Medical science Candidate: Magdaléna And lová Supervisor: Mgr. Marcela Vejsová, Ph.D. Name of diploma thesis: Evaluation of activity of potentional antibacterial substances throught of the use microdilution broth metod Background Aim of this diploma work was research of activity of potentional antimicrobiotic substances. Research of antibacterial substances is one of the most important factor in pharmaceutic industry. The main reason is being the never stopping growth of bacterial resistence. Methods The microdilution broth metod was used to test the substances. This metod was used because of low difficulty and low cost. All the steps including the final analising was done by hand. Results The substances were divided in groups depending their chemical struction. The most effective was the salicylanilide derivates group. The other groups inhibitated growth of bacteria very little or were non-functional. In case of every bacterial stems were analised all substances which were effective. Conclusion Depending on the results the most sensitive and the most resistant bacterial stem were choosen. The most sensitive reaction on tested substances had bacterial stem Staphylococcus aureus. The Klebsiella pneumoniae...
| Identifer | oai:union.ndltd.org:nusl.cz/oai:invenio.nusl.cz:350774 |
| Date | January 2016 |
| Creators | Andělová, Magdaléna |
| Contributors | Vejsová, Marcela, Jílek, Petr |
| Source Sets | Czech ETDs |
| Language | Czech |
| Detected Language | English |
| Type | info:eu-repo/semantics/masterThesis |
| Rights | info:eu-repo/semantics/restrictedAccess |
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