The neuroanatomical consequences of chronic ethanol ingestion were investigated using neuropsychological tests selectively sensitive to damage in circumscribed brain areas-~~~ The performance of a group of male alcoholics (N=15) with a self-reporte?- drinking history less than ten years, and a group of male alcoholics (N=15) with a self-reported drinking history of ten or more years was compared to a group of male nqnalcoholic controls (N=15). l.A--multiple covariate analysis was done prior to analyzing group differences to determine what influence three covariates (age, education and socioeconomic status) had on the group performances. Results from this analysis indicated that some of the tests were significantly influenced by age or education but no significant Group x Covariate interactions were observed. /JCn agreement with numerous neuropathological findings, the late stage alcoholics were found to be principally deteriorated on the tests of frontal lobe functioning, followed by lesser impairment on the tests of temporal lobe functioning, with no evidence of impairment on the tests of parietal lobe functioning~ No significant group differences were found betv1een the early stage alcoholics and the controls~ Small but negative correlations were found between both the duration of alcoholism and the average amount of alcohol consumed with each of the neuropsychological measures given in this study.
| Identifer | oai:union.ndltd.org:pacific.edu/oai:scholarlycommons.pacific.edu:uop_etds-2998 |
| Date | 01 January 1979 |
| Creators | Bolter, John Francis |
| Publisher | Scholarly Commons |
| Source Sets | University of the Pacific |
| Detected Language | English |
| Type | text |
| Format | application/pdf |
| Source | University of the Pacific Theses and Dissertations |
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