<p> </p>
<p>Conventional clinical therapies for head and neck squamous cell carcinomas (HNSCC) include surgical resection, chemotherapy (CT), and radiotherapy (RT). For locally advanced HNSCC, the CT-RT combination (“chemoradiation”) has been shown to be more effective than CT or RT alone and is the current standard of care. A novel radiation-controlled drug release nanoparticle formulation has been developed to realize the maximum benefits of intratumoral CT-RT. Under the application of low-dose X-ray, the formulation is capable of releasing PTX and providing localized, controlled, and sustained drug release for improvements in therapeutic efficacies.</p>
| Identifer | oai:union.ndltd.org:purdue.edu/oai:figshare.com:article/20405805 |
| Date | 29 July 2022 |
| Creators | Kaustabh Sarkar (13171509) |
| Source Sets | Purdue University |
| Detected Language | English |
| Type | Text, Thesis |
| Rights | CC BY 4.0 |
| Relation | https://figshare.com/articles/thesis/RADIOLUMINESCENT_NANOPARTICLES_FOR_MULTIMODAL_CANCER_TREATMENT/20405805 |
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