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Proton dose assessment to the human eye using Monte Carlo n-particle transport code (MCNPX)

The objective of this project was to develop a simple MCNPX model of the
human eye to approximate dose delivered from proton therapy. The calculated dose
included that due to proton interactions and secondary interactions, which included
multiple coulombic energy scattering, elastic and inelastic scattering, and non-elastic
nuclear reactions (i.e., the production of secondary particles). After benchmarking
MCNPX with a known proton simulation, the proton therapy beam used at Laboratori
Nazionali del Sud-INFN was modeled for simulation. A virtual water phantom was used
and energy tallies were found to correspond with the direct measurements from the
therapy beam in Italy. A simple eye model was constructed and combined with the
proton beam to measure dose distributions. Two treatment simulations were considered.
The first simulation was a typical treatment scenario-where dose was maximized to a
tumor volume and minimized elsewhere. The second case was a worst case scenario to
simulate a patient gazing directly into the treatment beam during therapy. Dose
distributions for the typical treatment yielded what was expected, but the worst case
scenario showed the bulk of dose deposited in the cornea and lens region. The study
concluded that MCNPX is a capable platform for patient planning but laborious for
programming multiple simulation configurations.
Date15 May 2009
CreatorsOertli, David Bernhardt
ContributorsFord, John R.
Source SetsTexas A and M University
Detected LanguageEnglish
TypeBook, Thesis, Electronic Thesis, text
Formatelectronic, application/pdf, born digital

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