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Multi-layer diffusion approximation for photon transport in biological tissue

A method for improving the accuracy of the optical diffusion theory for a multi-layer
scattering medium is presented. An infinitesimally narrow incident light beam is
replaced by multiple isotropic point sources of different strengths that are placed in the
scattering medium along the incident beam. The multiple sources are then used to
develop a multi-layer diffusion theory. Diffuse reflectance is then computed using the
multi-layer diffusion theory and compared with accurate data computed by the Monte
Carlo method. This multi-source method is found to be significantly more accurate than
the previous single-source method. The appendix to this thesis also shows the derivation
of the extrapolated boundary condition. This boundary condition is utilized to solve for
the discontinuity that occurs at the tissue-ambient medium interface. The boundary
conditions for common index of refraction mismatches are solved for and listed in a
table.

Identiferoai:union.ndltd.org:tamu.edu/oai:repository.tamu.edu:1969.1/ETD-TAMU-1901
Date02 June 2009
CreatorsHollmann, Joseph
ContributorsWang, Lihong
Source SetsTexas A and M University
Languageen_US
Detected LanguageEnglish
TypeBook, Thesis, Electronic Thesis, text
Formatelectronic, application/pdf, born digital

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