The objectives of this study were to identify signatures of selection in Bos taurus
beef and dairy cattle populations and to annotate regions of selection with gene, function
and QTL information. Differences in minor allele frequencies, population-average FST,
population-specific FST, and integrated extended haplotype homozygosity scores were
applied to a subset of the bovine HapMap data to characterize signatures of selection in 7
Bos taurus beef and 5 Bos taurus dairy cattle populations.
Numerous single nucleotide polymorphisms (SNP) exhibited evidence of
selection across the genome and regions of BTA2 and BTA14 that are considered to be
under positive selection in beef and dairy cattle, respectively, were highlighted. The
current density of SNP limited our ability to annotate regions putatively under selection
because most SNP in the assay were intergenic. This is likely because of the betweenbreed
SNP discovery method that was used, which typically identifies SNP with higher
allele frequencies.
| Identifer | oai:union.ndltd.org:tamu.edu/oai:repository.tamu.edu:1969.1/ETD-TAMU-2009-08-7166 |
| Date | 2009 August 1900 |
| Creators | Choi, Jung Woo |
| Contributors | Gill, Clare A. |
| Source Sets | Texas A and M University |
| Language | en_US |
| Detected Language | English |
| Type | Book, Thesis, Electronic Dissertation, text |
| Format | application/pdf |
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