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The Effect of Steroid Dose Regimen on the Relationship Between Lower Extremity Muscle Function and Cardiac Function in Post Heart Transplant Patients

Differences in cardiovascular/aerobic function in heart transplant patients might be attributed to the rate of corticosteroid withdrawal and/or to skeletal muscle function. This hypothesis was tested among nine male, cardiac transplant recipients. Prednisone dosage was monitored, and isokinetic strength testing was performed at 4 different time periods throughout the first year post-transplantation. Cardiovascular/aerobic measurements were obtained at the fourth time period. Pre-surgery characteristics were obtained from the patient's medical record. Significant Pearson-product moment correlations were only found between muscle function and aerobic function and between pre-surgery characteristics and cardiovascular/aerobic performance. The results of this study show no evidence that rapid reduction of prednisone dosage enhances aerobic function by benefiting skeletal muscle function.

Identiferoai:union.ndltd.org:unt.edu/info:ark/67531/metadc2761
Date05 1900
CreatorsGalatas, Mary V.
ContributorsHill, David W., Goggin, Noreen, Koziris, L. Perry
PublisherUniversity of North Texas
Source SetsUniversity of North Texas
LanguageEnglish
Detected LanguageEnglish
TypeThesis or Dissertation
FormatText
RightsUse restricted to UNT Community, Copyright, Galatas, Mary V., Copyright is held by the author, unless otherwise noted. All rights reserved.

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