The introduction of heteroartoms in the pyrazine portion of the pteridine ring has produced compounds which display antifolate activity. The initial objective of this research program was to develop a convenient synthesis of the 8-oxadihydropteridine ring system and to test the resulting compounds for antifolate activity in suitable biological systems.
| Identifer | oai:union.ndltd.org:unt.edu/info:ark/67531/metadc332795 |
| Date | 05 1900 |
| Creators | Dunn, Danny LeRoy |
| Publisher | North Texas State University |
| Source Sets | University of North Texas |
| Language | English |
| Detected Language | English |
| Type | Thesis or Dissertation |
| Format | Text |
| Rights | Public, ..., Copyright, Copyright is held by the author, unless otherwise noted. All rights reserved. |
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