A Differentiation Factor (DF) was purified from rat lung conditioned medium by a four-steps procedure. The DF has a molecular weight of 27000, and an isoelectric point of 4.70. Although DF is stable up to 60°C, it is sensitive to digestion by trypsin, chymotrypsin and subtilisin. DF forms granulocyte colonies in soft agar. Studies using anti-NRK CSF antibody demonstrated that DF is distinct from GM-CSF.
| Identifer | oai:union.ndltd.org:unt.edu/info:ark/67531/metadc798062 |
| Date | 05 1900 |
| Creators | Ansari, Naser A. (Naser Awni) |
| Publisher | North Texas State University |
| Source Sets | University of North Texas |
| Language | English |
| Detected Language | English |
| Type | Thesis or Dissertation |
| Format | vii, 73 leaves : ill., Text |
| Rights | Public, Ansari, Naser A. (Naser Awni), Copyright, Copyright is held by the author, unless otherwise noted. All rights |
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