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A Proposed Molecular Mechanism for the Activation of a Calcium/Phospholipid-Dependent Protein Kinase in P1798 Lymphosarcoma

Calcium/phospholipid-dependent protein kinase (PKC) was purified from P1798 lymphosarcoma. It was demonstrated that uncomplexed calcium and uncomplexed phosphatidylserine are the activators, that the activation of PKC requires that calcium bind first, that the activation of PKC requires that calcium bind first, that high calcium concentrations inhibit PKC activation, and that calcium inhibition can be overcome by phosphatidylserine.

Identiferoai:union.ndltd.org:unt.edu/info:ark/67531/metadc798423
Date05 1900
CreatorsElson, James L.
PublisherNorth Texas State University
Source SetsUniversity of North Texas
LanguageEnglish
Detected LanguageEnglish
TypeThesis or Dissertation
FormatText
RightsPublic, Copyright, Copyright is held by the author, unless otherwise noted. All rights

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