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Network Electrophysiology Sensor-On-A- Chip

"
Electroencephalogram (EEG), Electrocardiogram (ECG), and Electromyogram (EMG) bio-potential signals are commonly recorded in clinical practice. Typically, patients are connected to a bulky and mains-powered instrument, which reduces their mobility and creates discomfort. This limits the acquisition time, prevents the continuous monitoring of patients, and can affect the diagnosis of illness. Therefore, there is a great demand for low-power, small-size, and ambulatory bio-potential signal acquisition systems.
Recent work on instrumentation amplifier design for bio-potential signals can be broadly classified as using one or both of two popular techniques: In the first, an AC-coupled signal path with a MOS-Bipolar pseudo resistor is used to obtain a low-frequency cutoff that passes the signal of interest while rejecting large dc offsets. In the second, a chopper stabilization technique is designed to reduce 1/f noise at low frequencies. However, both of these existing techniques lack control of low-frequency cutoff.
This thesis presents the design of a mixed- signal integrated circuit (IC) prototype to provide complete, programmable analog signal conditioning and analog-to-digital conversion of an electrophysiologic signal. A front-end amplifier is designed with low input referred noise of 1 uVrms, and common mode rejection ratio 102 dB. A novel second order sigma-delta analog- to-digital converter (ADC) with a feedback integrator from the sigma-delta output is presented to program the low-frequency cutoff, and to enable wide input common mode range of ¡Ãƒâ€œ0.3 V. The overall system is implemented in Jazz Semiconductor 0.18 um CMOS technology with power consumption 5.8 mW from ¡Ãƒâ€œ0.9V power supplies. "

Identiferoai:union.ndltd.org:wpi.edu/oai:digitalcommons.wpi.edu:etd-dissertations-1388
Date29 September 2011
CreatorsChen, Tsai Yuan
ContributorsMichael Coln, Committee Member, Edward A. Clancy, Committee Member, John A. McNeill, Advisor
PublisherDigital WPI
Source SetsWorcester Polytechnic Institute
Detected LanguageEnglish
Typetext
Formatapplication/pdf
SourceDoctoral Dissertations (All Dissertations, All Years)

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