Thesis (Ph. D.)--West Virginia University, 2002. / Title from document title page. Document formatted into pages; contains x, 224 p. : ill. (some col.). Vita. Includes abstract. Includes bibliographical references.

Thesis (Ph. D.)--University of Hong Kong, 2005. / Title proper from title frame. Also available in printed format.

Thesis (M.D.)--University of Hong Kong, 1988. / Also available in print.

Thesis (Ph. D.)--University of Hong Kong, 2006. / Title proper from title frame. Also available in printed format.

Thesis (M.A.) -- Central Connecticut State University, 2007. / Thesis advisor: Thomas R King. "... in partial fulfillment of the requirements for the degree of Master of Arts in Biomolecular Sciences." Includes bibliographical references (leaves 29-30). Also available via the World Wide Web.

Thesis (Ph. D.)--Case Western Reserve University, 2007. / [School of Medicine] Department of Genetics. Includes bibliographical references. Available online via OhioLINK's ETD Center.

Bibliography: leaves 135-151. A study of chromosomal abnormalities and the localisation of chromosomes in human sperm, especially from men with TSD, using fluorescence in situ hybridization (FISH). The project entailed: 1. development of reliable FISH protocols, 2. determination of basline frequencies of aneuploidy, 3. analysis of chromosomal abnormalities in men with severe TSD and 4. assessment of the localisation of individual chromosomes within the sperm head.

The frequency of chromosome breaks was increased in replicate cultures from each of ten individuals when lysergic acid diethylamide at a concentration of 1 ug/ml of culture was added 24 hours prior to the harvest of the cells. The differences between the control and treated cultures ranged from +3.00 to +7.93 with a mean of +4.63, indicating no variation in response between individuals. The breaks were randomly distributed among the seven groups of chromosomes of the complement. No significant difference in either the number of cells with aberrations, or the number of breakage events was observed between cells cultured from a patient with Fanconi's anaemia before and 24 hours after treatment with 250 ug. of growth hormone. Both were significantly increased over the control. After treatment with growth hormone, the number of breaks per aberrant cell was decreased, and the distribution of frequencies of specific types of aberrations was changed. Non-homologous exchange figures were the only two break events observed in cultures from the patient. None were observed in control cells. The distribution of breaks among the seven groups of chromosomes was random. The frequency of chromosome aberrations was increased in cultures from a single individual when treated with 1 ug/ml of mitomycin-C for one hour at the beginning of the culture period. In the treated cultures, 181 breaks were observed in 64 of the 100 cells examined, whereas only 5 breaks were observed in three of the 100 cells scored in the control samples. Forty-seven exchange configurations were observed in the treated cultures, 42.56% of these being non-homologous exchanges. No marker or dicentric chromosomes were observed. Breaks were randomly distributed among the seven groups of chromosomes of the complement. / Medicine, Faculty of / Medical Genetics, Department of / Graduate

Cotton is a valuable fiber crop around the world used to create fabrics, oils, and currency. The threat of herbicide resistant (HR) weed populations is precarious for cotton production. The overreaching objective of this study was to phenotype potentially allelopathic chromosome substitution (CS) lines to determine competitive accessions. The identification of competitive cotton lines would be useful in the development of alternative weed control tools. Twelve CS lines (CS-49, CS-38, CS-34, CS-39, CS-27, CS-13, CS-50, CS-26, CS-25, CS-43, CS-46, and CS-23) along with the parent line (TM1) and two conventional varieties (UA48 and Enlist) were screened in a greenhouse using the stairstep structure. Eight CS lines were then selected to test in the field and analyzed in the lab to identify allelochemical exudates using HPLC. Results of this study provide a greater insight into the nature of allelopathy and its potential usefulness in cotton crops.

No description available.