61 |
Salmonella infection in the rat : the role of type 1 fimbriaeNaughton, Patrick J. January 1998 (has links)
Infection by <I>Salmonella enteritidis </I>and <I>S. typhimurium</I> has been studied in the rat (Hooded Lister) model <I>in vivo</I>. Salmonellosis in the Hooded Lister rat has many similarities with the disease in humans. <I>Salmonellae</I> associated with the small intestinal epithelium as early as 4 h after intragastric intubation. Therefore, reinfection from the large intestine initially may not play a significant role in the infection process. Both <I>Salmonella</I> serotypes colonised, persisted and proliferated in the gastrointestinal tract and invaded sub-epithelial tissues, mainly via the ileum, leading to the systemic distribution of these pathogens. Coincidental with the infection, polyamine levels and crypt cell proliferation rates in the small intestine increased resulting in substantial growth of the tissue. This growth was particularly dramatic in the ileum where there was also some disruption of the villous epithelium. It is possible that these effects of the infection on the metabolism and morphology of the small bowel, which strongly resembles the changes induced by some plant lectins, may facilitate the colonisation and invasion of the gut by <I>Salmonella sp.</I> It was shown for the first time, that <I>S. enteritidis</I> and <I>S. typhimurium</I> strains expressing type 1 fimbriae closely associated with the rat ileal epithelium <I>in vivo</I>. Moreover, orally administered purified type 1 fimbriae also associated with the ileal surface. Thus, type 1 fimbriae alone or in combination with other fimbriae may play an important role in the early stages of infection with these pathogenic bacteria. This was further supported by the finding that deletion of the type 1 fimbriae from a strain of <I>S. enteritidis</I> led to a reduction in the numbers of <I>Salmonella </I>present in the distal ileum 6 h post-dosing. The deletion of type 1 fimbriae did not however affect the long-term progression of infection, suggesting that type 1 fimbriae do not play a prominent role in persistence.
|
62 |
Molecular characterization and expression of Gq/11 protein in fishesRadhakrishnan, Varsha, January 2007 (has links)
Thesis (M.S.)--Texas State University-San Marcos, 2007. / Vita. Includes bibliographical references (leaves 68-75).
|
63 |
Tight junction in ovarian surface epithelium and epithelial ovarian tumors /Zhu, Yihong, January 2007 (has links)
Diss. (sammanfattning) Göteborg : Göteborgs universitet, 2007. / Härtill 4 uppsatser.
|
64 |
Genetic and molecular regulation of epithelial tube morphogenesis /Tonning, Anna, January 2006 (has links)
Diss. (sammanfattning) Göteborg : Göteborgs universitet, 2006. / Härtill 4 uppsatser.
|
65 |
Esophageal carcinogenesis immortalization, transformation and epithelial-mesenchymal transition /Cheung, Pak-yan. January 2008 (has links)
Thesis (Ph. D.)--University of Hong Kong, 2008. / Includes bibliographical references (leaves 207-242) Also available in print.
|
66 |
Epithelial remnants in the developing periodontium of mice a thesis submitted in partial fulfillment ... pedodontics ... /Maguire, John A. January 1975 (has links)
Thesis (M.S.)--University of Michigan, 1975.
|
67 |
Important role of tetraspanin CD81 in integrin-dependent retinal phagocytosis /Chang, Yongen. January 2007 (has links)
Thesis (Ph. D.)--Cornell University, May, 2007. / Vita. Includes bibliographical references (leaves 120-133).
|
68 |
Esophageal carcinogenesis : immortalization, transformation and epithelial-mesenchymal transition /Cheung, Pak-yan. January 2008 (has links)
Thesis (Ph. D.)--University of Hong Kong, 2008. / Includes bibliographical references (leaves 207-242) Also available online.
|
69 |
Cell population kinetics of the gingival epitheliumSkougaard, Mogens. January 1965 (has links)
Thesis--Copenhagen. / Bibliography: p. 127-134.
|
70 |
Early detection of curable precancerous lesions in the oral cavity using polarized reflectance spectroscopyNieman, Linda Tae. Sokolov, Konstantin, Raizen, Mark George, January 2004 (has links) (PDF)
Thesis (Ph. D.)--University of Texas at Austin, 2004. / Supervisors: Konstantin Sokolov and Mark Raizen. Vita. Includes bibliographical references. Also available from UMI.
|
Page generated in 0.0558 seconds