京都大学 / 0048 / 新制・課程博士 / 博士(医学) / 甲第22339号 / 医博第4580号 / 新制||医||1042(附属図書館) / 京都大学大学院医学研究科医学専攻 / (主査)教授 木村 剛, 教授 髙橋 良輔, 教授 小池 薫 / 学位規則第4条第1項該当 / Doctor of Medical Science / Kyoto University / DFAM

京都大学 / 新制・課程博士 / 博士(医学) / 甲第23371号 / 医博第4740号 / 新制||医||1051(附属図書館) / 京都大学大学院医学研究科医学専攻 / (主査)教授 髙橋 良輔, 教授 安達 泰治, 教授 YOUSSEFIAN Shohab / 学位規則第4条第1項該当 / Doctor of Medical Science / Kyoto University / DFAM

This diploma thesis deals with the creation of computational model of arterial aneurysm, which respects its real geometry and constitutive behaviour. Subsequently there is explored the risk of rupture, comparing the values of the highest main stress in aneurysm´s and intact aorta´s wall. This thesis also offers the comprehensive summary and mutual comparision of current constitutive (hyperelastic) models, which are for simplicity isochoric considered. The main task of this thesis is to formulate the method for finding of „unloaded“ = „outstressed“ = „primary“ = reduced geometry, which is generally unavailable. Models of aneurysm´s geometry, used so far, present already deformed configurations from blood pressure, axial prestrech and rezidual strain.

No description available.

Knäets artär, arteria (a.) poplitea, kan drabbas av aneurysm, vanligen om personen redan har ett aortaaneurysm. Kärlväggen påverkas av träning på olika sätt. Enligt olika studier ökar eller minskar a. popliteas lumendiameter av aerob träning. Syftet med denna studie är att se om regelbunden aerob träning påverkar lumendiametern i a. poplitea. Med hjälp av ultraljud hararteria popliteas lumendiameter mätts hos totalt 31 frivilliga personer, där hälften var tränade och resten var otränade, både kvinnor och män. Insamlad data har analyserats med IBM SPSS version 27. Denna studie bekräftar det tidigare studier sagt, att män har större lumendiameter i a. poplitea än kvinnor. Lumendiametern i a. poplitea är större i dess proximala och mediala delar, än i dess distala del. Studien visar inga signifikanta skillnader i a. popliteas lumendiameter mellan personer som tränar regelbundet och otränade personer, det finns tendenser till att de som tränar har större lumendiameter. Det resultatet överensstämmer med några av de tidigare studierna, med tanke på denna studies storlek börstörre och mer omfattande studier behöver göras för säkrare resultat. / The artery in the knee, popliteal artery, can get an aneurysm, usually if the person already hasan aortic aneurysm. Vessels are affected by exercise in different ways. Various studies say that the lumen diameter in a. poplitea both increases and decreases with aerobic exercise. The purpose of this study is to see if regular aerobic exercise affects the diameter of the popliteal artery. Using ultrasound, the lumen diameter of the popliteal artery has been measured in trained and untrained women and men, in total 31 volunteers was examined. The collected data were then analysed with IBM SPSS version 27. This study confirms that men have larger lumen diameters in the popliteal artery than women. The lumen diameter of the popliteal artery is larger in its proximal and medial parts, than in the distal parts. This study has concluded thatthere is no significant difference in the popliteal artery's lumen diameter in trained and in untrained persons, however there is a tendency that trained persons have larger lumen diameters than untrained persons. That is consistent with some of the previous studies, but larger and more comprehensive studies need to be done for more accurate results.

京都大学 / 0048 / 新制・課程博士 / 博士(医学) / 甲第19397号 / 医博第4048号 / 新制||医||1012(附属図書館) / 32422 / 京都大学大学院医学研究科医学専攻 / (主査)教授 渡邊 直樹, 教授 小泉 昭夫, 教授 木村 剛 / 学位規則第4条第1項該当 / Doctor of Medical Science / Kyoto University / DFAM

京都大学 / 0048 / 新制・課程博士 / 博士(医学) / 甲第20236号 / 医博第4195号 / 新制||医||1019(附属図書館) / 京都大学大学院医学研究科医学専攻 / (主査)教授 木村 剛, 教授 松原 和夫, 教授 川村 孝 / 学位規則第4条第1項該当 / Doctor of Medical Science / Kyoto University / DFAM

Introduction: Haemodialysis arterio-venous fistula aneurysm (AAVF) prevalence varies between 7-43%. When they are symptomatic, they should be referred for treatment. It is unclear which is the optimal surgical treatment and if fistula flow reduction is beneficial for heart remodeling in patients with high-flow AAVF. Aims: (1) introduction of a new surgical technique - aneurysmorrhaphy using exoprothesis (AuE) and evaluation of its patency and complication rates. (2) analysis of flow reduction impact on heart remodeling in high-flow AAVF. (3) systematic review and meta- analysis of various surgical techniques to identify the best treatment option of haemodialysis arterio-venous fistula aneurysm. Methods: (1) retrospective analysis with prospectively collected surgical and postoperative data, patency evaluation using Kaplan - Meier curve, early and late complication rates analysis. (2) retrospective analysis prospectively collected echocardiographic parameters before and after surgery. (3) systematic review and meta- analysis following the PRISMA guidelines - registered in the international prospective register of prospective reviews PROSPERO (registration number: CRD42016029692). Results: (1) primary assisted patency rate at 12 months was 80 %, infection rate was 4.5 % and AAVF recurrence rate was 0...

京都大学 / 新制・課程博士 / 博士(医学) / 甲第24785号 / 医博第4977号 / 新制||医||1066(附属図書館) / 京都大学大学院医学研究科医学専攻 / (主査)教授 金子 新, 教授 YOUSSEFIAN Shohab, 教授 阪上 優 / 学位規則第4条第1項該当 / Doctor of Medical Science / Kyoto University / DFAM

京都大学 / 新制・課程博士 / 博士(医学) / 甲第24484号 / 医博第4926号 / 新制||医||1063(附属図書館) / 京都大学大学院医学研究科医学専攻 / (主査)教授 森信 暁雄, 教授 YOUSSEFIAN Shohab, 教授 齊藤 博英 / 学位規則第4条第1項該当 / Doctor of Medical Science / Kyoto University / DFAM