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The Global ETD Search service is a free service for researchers
to find electronic theses and dissertations. This service is
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Networked Digital Library of Theses and Dissertations.
Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
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Showing 431 to 432 of 432 (0.025 seconds)Spelling suggestions: "subject:"[een] AORTA"" "subject:"[enn] AORTA""
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Phase Unwrapping MRI Flow Measurements / Fasutvikning av MRT-flödesmätningarLiljeblad, Mio January 2023 (has links)
Magnetic resonance images (MRI) are acquired by sampling the current of induced electromotiveforce (EMF). EMF is induced due to flux of the net magnetic field from coherent nuclear spins with intrinsic magnetic dipole moments. The spins are excited by (non-ionizing) radio frequency electromagnetic radiation in conjunction with stationary and gradient magnetic fields. These images reveal detailed internal morphological structures as well as enable functional assessment of the body that can help diagnose a wide range of medical conditions. The aim of this project was to unwrap phase contrast cine magnetic resonance images, targeting the great vessels. The maximum encoded velocity (venc) is limited to the angular phase range [-π, π] radians. This may result in aliasing if the venc is set too low by the MRI personnel. Aliased images yield inaccurate cardiac stroke volume measurements and therefore require acquisition retakes. The retakes might be avoided if the images could be unwrapped in post-processing instead. Using computer vision, the angular phase of flow measurements as well as the angular phase of retrospectively wrapped image sets were unwrapped. The performances of three algorithms were assessed, Laplacian algorithm, sequential tree-reweighted message passing and iterative graph cuts. The associated energy formulation was also evaluated. Iterative graph cuts was shown to be the most robust with respect to the number of wraps and the energies correlated with the errors. This thesis shows that there is potential to reduce the number of acquisition retakes, although the MRI personnel still need to verify that the unwrapping performances are satisfactory. Given the promising results of iterative graph cuts, next it would be valuable to investigate the performance of a globally optimal surface estimation algorithm.
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Third Place Winner of the Conrad Jobst Award in the Gold Medal Paper Competition. Prevention of Spinal Cord Dysfunction in a New Model of Spinal Cord IschemiaLopez, S, Manahan, E, Evans, J. R., Kao, R. L., Browder, W. 01 January 1995 (has links)
Paraplegia or paraparesis caused by temporary cross-clamping of the aorta is a devastating sequela in patients after surgery of the thoracoabdominal aorta. No effective clinical method is available to protect the spinal cord from ischemic reperfusion injury. A small animal (rat) model of spinal cord ischemia is established to better understand the pathophysiological events and to evaluate potential treatments. Eighty-one male Sprague-Dawley rats weighing 300 g to 350 g were used for model development (45) and treatment evaluation (36). The heparinized and anesthetized rat was supported by a respirator following tracheostomy. The thoracic aorta was cannulated via the left carotid artery for post-clamping intra-aortic treatment solution administration. After thoracotomy, the aorta was freed and temporarily clamped just distal to the left subclavian artery and just proximal to the diaphragm for different time intervals: 0, 5, 10, 15, 20, 25, 30, 35, and 40 minutes (five animals per group). The motor function of the lower extremities postoperatively showed consistent impairment after 30 minutes clamping (5/5 rats were paralyzed), and this time interval was used for treatment evaluation. For each treatment, six animals per group were used, and direct local intra-aortic infusion of physiologic solution (2 mL) at different temperatures with or without buffer substances was given immediately after double cross-clamp to protect the ischemic spinal cord. Arterial blood (2 mL) was infused in the control group. The data indicate that the addition of HCO3-(20 mM) to the hypothermic (15 degrees C) solution offered complete protection of the spinal cord from ischemic injury.(ABSTRACT TRUNCATED AT 250 WORDS)
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