京都大学 / 0048 / 新制・課程博士 / 博士(理学) / 甲第19883号 / 理博第4210号 / 新制||理||1605(附属図書館) / 32960 / 京都大学大学院理学研究科化学専攻 / (主査)教授 三木 邦夫, 教授 杉山 弘, 教授 藤井 紀子 / 学位規則第4条第1項該当 / Doctor of Science / Kyoto University / DGAM

Reflex inhibition of the quadriceps muscle group is a frequent and significant consequence of knee trauma, disease and surgical insult. The resultant quadriceps atrophy can be expected to delay rehabilitation and render the joint vulnerable to repeated injury resulting in capsular and synovial thickening, effusion and pain. A major purpose of this study was to examine the degree of quadriceps inhibition experienced by patients who undergo arthroscopic menisectomy. A secondary goal of this study was to investigate the efficacy of transcutaneous electrical nerve stimulation on the relief of reflex inhibition. Tests were performed on 12 patients prior to, and on day 1 and day 2 post surgery. True and placebo treatments of transcutaneous electrical nerve stimulation were administered on day 1 and day 2 post surgery. Measurements were made on the injured and normal limb with the knee fixed at 38G of flexion. Motor unit activation was determined by the twitch interpolation technique. Reduced motor unit activation was considered indicative of quadriceps reflex inhibition. Testing demonstrated that at all times the injured leg was weaker than the normal leg (p=.OOl). Following surgery, strength of the injured limb was significantly less than its pre operative score (p=.Ol). No significant recovery of strength was observed during the first two days following surgery. Injured legs were characterized by significantly lower motor unit activation at all times of testing Cp=.003). Following surgery, motor unit activation for the injured leg was significantly lower than its pre operative value (p=.Ol). By day 2 post surgery, motor unit activation had recovered Cp=.05) and was similar to the pre operative values for that leg. Transcutaneous electrical nerve stimulation had no effect on strength or motor unit activation. Recovery following arthroscopic surgery is characterized by an initial loss of strength and motor unit activation. By day 2, isometric strength remains depressed, however motor unit activation returns to pre surgery levels. / Thesis / Master of Science (MSc)

published_or_final_version / Psychology / Doctoral / Doctor of Philosophy

To achieve goal-orientated behaviour, selective attention is often needed to filter out irrelevant information. Past research has shown that working memory (WM) plays a critical role in selective attention, with high WM load leading to more distractor interference than low WM load. However, because WM load is usually manipulated by requiring participants to hold in memory either one or several digits that were presented simultaneously while performing a selective attention task, the extent of attentional focus was not controlled. The present study examined the effect of WM load on distractor inhibition while keeping attentional focus constant by presenting one digit (low load condition) or six digits (high load condition) sequentially. The participants in the high-load condition demonstrated greater distractor interference than the participants in the low-load condition, suggesting that WM load influences distractor inhibition even when the extent of attentional focus was controlled. This result provides converging evidence to Lavie's (1995, 2005) load theory of attention and cognitive control.

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