濃度3Mの硝酸亜鉛水溶液中170°Cで7 h水熱処理し，ついで大気中600℃で再酸化処理して合成した酸化亜鉛ZnOは持続的な暗所抗菌性を示す．このZnOについて物理化学な物性を詳細に検討した．また，カリウムKとりんPを1:3の原子比率で添加固溶させたアナターゼ型酸化チタンTiO2は暗所でも抗菌性を示すことを新たに見出した．その抗菌性発現のメカニズムについて検討した結果を報告する． / Both ZnO and TiO2 have high potential as antibacterial agents which are able to apply in various fields. Although there are already many studies about these materials focusing on their antibacterial activity, they are still getting more attention from researchers due to their unclear mechanism under dark. There have been very few reports mentioning clearly about this. Besides, the effects of the preparation methods and their physicochemical properties to the antibacterial property of ZnO, TiO2 and doped TiO2 under dark also have not been well-characterized. In the present study, synthesis and physicochemical evaluation of metal oxides which reveal antibacterial activity even in the dark conditions have been performed. / 博士(工学) / Doctor of Philosophy in Engineering / 同志社大学 / Doshisha University