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Intermolecular Addition Of Aldehydes To Ketones Via Acyl PhosphonatesEsiringu, Ilker 01 April 2008 (has links) (PDF)
This thesis presents a new developed method for first intermolecular aldehyde/ketone cross benzoin coupling. Protected & / #945 / -keto tertiary alcohols are synthesized starting from easily available acyl phosphonates and ketones via Brook rearrangement in the presence of catalytic amount of cyanide ion. The scopes and the limitations of the methods for the synthesis of tertiary alcohols with & / #945 / -keto group are discovered.
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