Text in English / It is common knowledge that the social work profession in Africa, including its theories, methods, and models, has been implanted from the global North (Europe) and North America. Scholarship within social work has confirmed that there are challenges of relevance and appropriateness of Westernised social work interventions, and consequently, their effectiveness in a context outside the Euro-North American axis. It is against this backdrop that the researcher explored the African family, its experiences, and its coping strategies when raising a child with Down syndrome as well as the nature of social work services they received and whether such services were congruent with the family’s existential condition and subjectivities. A retrospective qualitative study following a phenomenological design was conducted. Research data were collected from a sample drawn using purposive and snowball techniques, through the use of semi-structured interviews. Qualitative data analysis process adapted from Terre Blanche, Durrheim and Painter (2006:33) was used. The findings revealed the existence of a paradoxical relationship between Eurocentrism underlying social work practice and the Afrocentric worldview. The typical African family raising a child with DS was found to be characterised by a unique form and structure consistent with a clan system different from the conventional Eurocentric concept of family. It was also found that despite the pressure and assault exerted by modernity, colonization and apartheid on the traditional African clan system, it remained resilient and retained its unique character distinct from the western nuclear family system. In relation to dealing with challenges associated with raising a child with DS, the African clan’s concerns were found to transcend pre-occupation with the etiology and treatment of the condition as emphasized in the western paradigm. Without discounting the significance of the etiology and treatment of the condition, the African clan draws on its spirituality and affection to consider the purpose and function of the condition in the bigger scheme of things. Social work as a helping profession seemed to be unpopular amongst African clans raising children with DS. The findings were used to develop indigenised social work practice guidelines for social workers assisting African families raising children with DS. / Social Work / Ph. D. (Social Work)