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The Global ETD Search service is a free service for researchers
to find electronic theses and dissertations. This service is
provided by the
Networked Digital Library of Theses and Dissertations.
Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
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Showing 1 to 10 of 28 (0.013 seconds)| 1 |
Studies on the generation and use of functionalised organozinc carbenoids for the synthesis of aminocyclopropanes and related congenersBégis, Guillaume January 2004 (has links)
The present thesis describes a range of studies on the generation and reactivity of organozinc carbenoid species possessing adjacent nitrogen functionality for the preparation of aminocyclopropanes and related congeners. This thesis opens with two distinct introductory reviews. The first one focuses on the description of the different general methods already available for the synthesis of aminocyclopropanes. The second one is concerned with the generation and reactivity of organozinc carbenoids encountered in the literature. The results and discussion chapter firstly describes the successful generation of an organozinc carbenoid from an acetal moiety contiguous to a nitrogen atom of a simple cyclic amide using a mixture of zinc amalgam and chlorotrimethylsilane. This new organometallic species is found to undergo cyclopropanation reactions with a range of alkenes to yield amidocyclopropanes. Subsequent studies directed towards the design of carbenoid precursors which can lead to the preparation of primary aminocyclopropanes are then discussed. A method for the synthesis of chiral protected aminocyclopropanes in two steps from their corresponding alkenes is described. An investigation of the preparation of N-substituted cyclopropyl amino alcohols and acids is presented. From this study, an N-substituted cyclopropyl glycine derivative is prepared. Finally, this thesis discusses the attempted palladium-catalysed cross-coupling reactions between amino cyclopropylsilanes and aryl iodides and the successful Tamao-Fleming oxidation of the carbon-silicon bond of vicinal amino cyclopropylsilanols to give the corresponding amino cyclopropanols. The thesis terminates with a full description of the experimental procedures used and the compounds prepared.
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Stereochemical control in cyclopropanation reactions mediated by sulfonium ylidesGrange, Emma January 2006 (has links)
No description available.
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Novel oilfield polymers via transesterification reactionsDrummond, Graham R. January 2007 (has links)
No description available.
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A novel approach to the synthesis of spiropyrrolidinyloxindole alkaloidsWright, Andrew G. January 2004 (has links)
No description available.
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New routes to medium ring lactones and ethers of biological interestEdwards, Simon D. January 1999 (has links)
No description available.
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Cloning and directed evolution of hydrolytic enzymes for deracemisation of enol estersParsy, CeÌline January 2004 (has links)
No description available.
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Transition metal catalysed homogeneous hydroamination, allylic substitution and transfer hydrogenation reactionsCheng, Xiaohui January 2003 (has links)
No description available.
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Studies on O-alkylisoureas in solution phase and on solid supportCrosignani, Stefano January 2003 (has links)
No description available.
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Thiophosphates : Co(III) and hydroxide catalysed hydrolysisPadovani, Michela January 2003 (has links)
No description available.
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Novel oxaziridines for asymmetric electrophilic aminationEdmonds, Ian David January 2004 (has links)
No description available.
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