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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
41

The causes and consequences of variation in evolutionary processes acting on DNA sequences

Bofkin, Lee Nathan Marc January 2006 (has links)
No description available.
42

Genome assembly and comparison using de Bruijn graphs

Zerbino, Daniel Robert January 2009 (has links)
No description available.
43

Applications of combinatorial pattern discovery in computational genomics

Darzentas, Nikos January 2006 (has links)
No description available.
44

Transcriptional and post-transcriptional regulation of gene expression : computational analysis of microarray studies in fungal species

Lawler, Katherine Joanne January 2010 (has links)
No description available.
45

Function and evolution of regulatory elements in vertebrates

Meynert, Alison Maria January 2010 (has links)
No description available.
46

Automatic functional annotation of predicted active sites : combining PDB and literature mining

Nagel, Kevin January 2010 (has links)
No description available.
47

A computational study of bacterial gene regulation and adaptation on a genomic scale

Seshasayee, Aswin Sai Narain January 2009 (has links)
No description available.
48

Computational analysis of protein interactions and interfaces

Kim, Wan Kyu January 2007 (has links)
No description available.
49

Novel algorithms for protein interaction networks

Lappe, Michael January 2004 (has links)
No description available.
50

Role and application of ontology design patterns in bio-ontologies

Aranguren, Mikel Egaña January 2009 (has links)
Knowledge Representation (KR) languages such as OWL (Web Ontology Languge), having precise semantics, offer the possibility of computationally exploiting biological knowledge, by codifying it in the axioms of bio-ontologies widely used in life sciences for knowledge management. Knowledge is, however, often represented in bio-ontologies without following rigorous principles of modelling and the resulting bio-ontologies are axiomatically lean. Therefore knowledge cannot be computationally exploited for integrity checking, hypothesis generation, consistency maintenance, integration, or rich querying. A solution that can contribute to the rigorous modelling and axiomatic richness of bio-ontologies is is the use of Ontology Design Patterns (ODPs). ODPs are thoroughly documented and efficient solutions for recurrent problems encountered when building ontologies. Therefore ODPs act as guides on how to use KR languages for creating ontology fragments that have well known advantages and side effects. In order forr ODPs to be efficiently accessed by bio-ontologists, an online catalogue of ODPs has been created, describing different ODPs using a consisistent documentation schema. Such ODPs, apart from being accessed, can be applied automatatically with the Ontology Preprocessor Language (OPPL), as OPPL makes it possible to encapsulate ODPs in scripts to be executed on OWL ontologies, making the application of ODPs replicable and flexible. The infrastructure for applying ODPs formed by the catalogue amd OPPL has been used for applying ODPs in bio-ontologies like the Cell Type Ontology. The results of such application have been evaluated to assess the applied ODPs and the chang on ontology quality.

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