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Biochemical characterisation of Nicotiana tabacum over-expressing mitochondrial matrix located HSP70Dorling, Sarah January 2005 (has links)
No description available.
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Structure and function relationships of mutations in human melanocortin receptors 1 and 2Doufexis, Marina January 2003 (has links)
No description available.
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Reverse engineering of GroEL : an investigation of the mechanistic behaviour of a single-ring variantPoso, Daniel January 2004 (has links)
No description available.
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Interactions between proteins involved in mammalian endocytic and secretory pathwaysOakley, Jacqueline D. January 2004 (has links)
No description available.
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Consequences of BAG-1 isoform over-expression on keratinocyte motility and stratificationPage, Charlotte Anne Margaret January 2007 (has links)
No description available.
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Computational protein structure prediction using physico-chemical force fields : assessing reduced-atom and torsional models for accelerating the phase-space search processBrewer, Allan Ronald January 2005 (has links)
No description available.
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Low molecular weight proteomic analysis of Arabidopsis thaliana and Oryza sativa seedsGriffin, Jonathan Hrothgar January 2005 (has links)
No description available.
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Properties of the nicotinic acid adenine dinucleotide phosphate-binding protein in sea urchin eggsChuramani, Dev January 2006 (has links)
Nicotinic acid adenine dinucleotide phosphate (NAADP) has recently emerged as a novel intracellular calcium mobilising messenger in a variety of cells. Whilst increasing evidence suggests that NAADP acts on a distinct binding protein, little is known regarding the biochemical properties of the putative NAADP "receptor". My thesis investigates properties of the NAADP-binding protein in sea urchin eggs. Firstly, I show that NAADP binding to its target protein is inhibited by altering the protein:lipid ratio of soluble sea urchin egg homogenates - an effect prevented and reversed specifically by addition of exogenous phospholipids. These data highlight the importance of the lipid environment in maintenance of NAADP binding to its target protein. In addition, I show that upon binding its ligand, the NAADP-binding protein undergoes an unusual stabilization process that is dependent upon the time the receptor is exposed to its ligand. This property endows the NAADP-binding protein with the extraordinary ability to detect the duration of its activation. Finally I describe the development of a highly sensitive radioreceptor assay (based upon the sea urchin egg NAADP-binding protein) that is capable of detecting low levels of NAADP from cellular extracts. I apply this technique to determine NAADP levels in a variety of extracts prepared from cells under resting and stimulated conditions.
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Recognition of distinctive features in protein structures using correlation matrix memoriesBarker, Oliver Robin January 2004 (has links)
No description available.
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Molecular mechanisms of clathrin coat formation in neuroendocrine cellsHinners, Ina January 2003 (has links)
No description available.
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