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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
91

Dopamine receptor signalling to GABA subscription A) receptors:bRegulation of cell-surface expression levels and GABAergic synapse formation

Goffin, Darren January 2009 (has links)
No description available.
92

The regulation of Kv4.2 and KChIP1 trafficking to the plasma emebrane

Flowerdew, Sarah Elizabeth January 2009 (has links)
No description available.
93

The generation and characterisation of DigLON-Fc (CO-Fc) recombinant protein and its interactions with the putative neuronal receptors

Akeel, Mohammed Abdulraheem Mohammed January 2010 (has links)
No description available.
94

Control of neural stem cell migration by electric fields

Arocena, Miguel January 2010 (has links)
Neural stem cells showed strong electrotaxis, evidenced by highly directed migration towards the cathode.  Optimal electrotaxis was found to require growth factors and phosphoinositide 3-kinase (PI3-K) signalling, although reduced electrotaxis could be obtained without growth factors at the highest EFs used.  After EF exposure, neural stem cell trajectories became much more linear, and a reduction in the number of cell protrusions oriented towards the anode was observed.  Also, protrusions initially orienting towards the cathode retracted after the polarity of the EF was reversed, suggesting that EFs could inhibit the extension of anodal protrusions.  A simple model of neural stem cell migration was built with only two key parameters, which reproduced accurately neural stem cell migration patterns, and predicted that PI3-K functions in electrotaxis mainly by controlling cell orientation.  Finally, wild-type and <i>Pax6<sup>-/-</sup></i> embryonic neural stem cells were exposed simultaneously to EFs and contact guidance cues in conflicting orientations.  Only wild-type neural stem cells showed significant integrative migratory responses, suggesting that Pax6 is important for integration of diverse guidance cues during cell migration. The results obtained in this thesis show that neural stem cells display strong electrotaxis <i>in vitro</i>, which is accompanied by a qualitative change in the pattern of migration.  The results also identify the control of protrusion orientation by EFs as an important element in neural stem cell electrotaxis, contributing insight into the mechanisms of electrotaxis.  Finally, these results warrant further studies to assess the possibility of using EFs in brain repair therapies.
95

Investigation of the role of Id Helix-loop-helix proteins in neurogenesis

Yang, Jing January 2009 (has links)
No description available.
96

Molecular analyses of the bioactive components in snake venom

Guo, Chun Teng January 2006 (has links)
No description available.
97

Role of FGF receptors (FGFRs) in neurocytogenesis within the cerebral cortex

Sparshott, Neil January 2009 (has links)
No description available.
98

The role of cannabinoids in sensory gating : a neural network study

Zachariou, Margarita January 2008 (has links)
No description available.
99

Tyrosine phosphorylation of spectrin and its relation to neurite growth

Taupin, Hazel Lindsay January 2007 (has links)
No description available.
100

The role of serotonin and synaptic plasticity in the generation and modulation of hippocampal gamma-frequency (20-80Hz) oscillations in vitro

Eden, Dorcas Claudia January 2010 (has links)
No description available.

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