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This work is the first translation into a modern language of book 1 of the Libri Medicinales of Aëtius of Amida, a Byzantine physician who wrote in the middle of the 6th century AD. It comprises a lengthy preface, describing the analysis of pharmacological materials in terms of the science of the time, followed by 418 chapters, listing such materials obtained from plants. Commentary is to be found in the Introduction, as well as a running commentary after each part of the preface and each chapter. As Aëtius’ book 1 is a synopsis of the plants section of Galen’s On the Mixtures and Capacities of Simple Drugs, particular attention is paid to comparison between Aëtius’ work and that of Galen. Evaluation of the efficacy and safety of the ancient drugs in the light of modern scientific knowledge, a relatively neglected area of research, has also been given serious consideration.

Galen’s theory of black bile is strongly influenced by his aim to bring together a wide range of material from the work of different physicians and philosophers that begins with Hippocrates. This has caused there to be a large amount of inconsistencies in his writing on black bile. There has been a tendency in modern scholarship either to try to resolve these inconsistencies or to ignore them completely. In many cases there has been an emphasis on the definition of black bile in the Hippocratic On the Nature of Man as the most important basis for understanding Galen’s characterisation of black bile. My analysis will challenge this assumption concerning the dominance of On the Nature of Man for Galen’s use of black bile in his explanation of health and disease in the body. I shall show that an investigation of the way that Galen characterises the physical properties and function of black bile reveals that it is better to understand his use of this humour in terms of his attempt to bring material from a wide range of authorities together to support the arguments that he presents in his treatises. Galen defines black bile as three distinct types of substance that differ in physical properties in order to account for the different ways that this humour is characterised and defined in the various medical sources that he draws upon. However, he is unable to produce a theory of black bile without inconsistencies relating to a number of issues that include such factors as his naming of the different forms of black bile and his concept of authenticity of texts in the Hippocratic Corpus. Galen’s strategy is to make his audience believe that there is a comprehensive and well-defined theory of black bile that originates in the work of Hippocrates and was followed by certain physicians and philosophers afterwards. But in reality this is just a façade and Galen defines and uses black bile in many different and inconsistent ways for his arguments and refutations that cannot always be reconciled with the content of his sources.

This thesis presents the first steps towards a critical edition of the ‘De podagra’ (‘On Gout’), a pre-Gariopontean treatise excerpted from the Latin translation of the Greek ‘Therapeutica’ by Alexander of Tralles. From information collated, from manuscripts and printed texts, from four textual traditions, the Greek ‘Therapeutica’, the Latin Alexander, the ‘De podagra’, and Gariopontus’ ‘Passionarius’, a provisional Latin text of the ‘De podagra’ has been produced which looks forward to the last of these traditions, Gariopontus’ ‘Passionarius’. A full English translation of the ‘De podagra’ is given. The footnotes to the provisional Latin text of the ‘De podagra’ serve to illustrate the textual tradition and highlight points of relevance for the content of the text itself. These footnotes also contain information of significance to the reconstruction of each of the other three traditions. An appendix of ‘materia medica’ and an ‘index uerborum’ are included.