- About
-
The Global ETD Search service is a free service for researchers
to find electronic theses and dissertations. This service is
provided by the
Networked Digital Library of Theses and Dissertations.
Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
Search results
Showing 1001 to 1010 of 4832 (0.12 seconds)| 1001 |
Assessment of pharmacogenetic polymorphisms in haematopoietic stem cell transplantationPetropoulos, Antonios January 2009 (has links)
No description available.
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| 1002 |
Investigation of Neuronal Effects of Anxiogenic and Antidepressant Medications using Pharmacological Magnetic Resonance ImagingSekar, Sakthivel January 2010 (has links)
No description available.
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| 1003 |
Systematic investigation of the inconsistent anorectic response to PYY3-36 in laboratory ratsHolch, Patricia January 2009 (has links)
No description available.
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| 1004 |
Modulation of endothelial cell calcium by glucose, insulin and gaseous transmittersBauer, Claudia christina January 2010 (has links)
No description available.
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| 1005 |
Rhodium and iridium-catalysed nucleophilic addition/substitution reactions for the synthesis of lead-like scaffoldsLi, Ho Yin January 2012 (has links)
The research project presented in this thesis aimed to synthesise lead-like scaffolds under array conditions utilizing a novel metal catalysed reaction sequence. The reaction sequence was designed to synthesize libraries of compounds with structural diversity and maximum functional group compatibility in order to aid organic synthesis in modern medicinal industry. The first part of this thesis involved the study of rhodium-catalysed conjugate addition of boronic acids/esters to various Michael acceptors. This methodology has been investigated in order to expand the nucleophile scope to ortho-substituted functionalised (hetero)arylboronic acids/esters for the synthesis of benzo-fused heterocycles in good yield and diastereoselectivity. The potential for asymmetric conjugate addition has been explored with limited success. The second part of this thesis involved the study of iridium-catalysed asymmetric allylic substitution of amines to allylic carbonates. The synthesis of chiral polyamine intermediates was achieved in good yield, regio- and stereoselectivity by using diamine nucleophiles. A limited study has been performed to investigate the potential divergent synthesis of small, polar, highly functionalized chiral molecules. It has been demonstrated that by applying both methodologies, libraries of 'structurally diverse compounds can be synthesised from a small number of starting materials.
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| 1006 |
Cellular and molecular mechanisms of non-response to anti-TNF therapy in rheumatoid arthritis patientsCoulthard, Lydia Ruth January 2009 (has links)
No description available.
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| 1007 |
Individual and combined effects of cannabinoid, opioid and monoaminergic compounds on food intake, behaviour and weight gain in ratsTallett, Amy Johanna January 2009 (has links)
No description available.
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| 1008 |
The role of the N-terminal domains of the CGRP receptor in binding peptide agonists and non-peptide antagonistsMiller, Philip Saxon January 2009 (has links)
No description available.
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| 1009 |
Antipsychotic modulation of cannabinoid signaling in the CNS and behavioral correlatesBurston, James Justin January 2009 (has links)
No description available.
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| 1010 |
Use of Bioluminescent Bacterial Biosensors to Study the Intracellular Metabolism of Anti-Cancer DrugsAngell, Johanna Elizabeth January 2010 (has links)
No description available.
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