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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
1491

Desensitisation of inhibitory G-protein-coupled responses in neuroblastoma cells

Hepworth, Mark Barrett January 1996 (has links)
No description available.
1492

The effects of kainate on the release of radiolabelled and endogenous glutamate in the rat hippocampus and cortex : an in vitro investigation using the isolated nerve terminal preparation

Chittajallu, Ramesh January 1997 (has links)
No description available.
1493

Ionotropic and metabotropic glutamate receptor functions in the spinal cord

Jones, Matthew Warwick January 1996 (has links)
No description available.
1494

Characterisation of dopamine D3 receptors in recombinant cell lines and rat brain

Large, Charles Henry January 1994 (has links)
No description available.
1495

A study of anticonvulsant action of sodium valporate

Dhariwal, Mohammad Ali Husnain January 1992 (has links)
No description available.
1496

Low frequency dielectric investigations on hydrated pharmaceutical powders

Pearson, David S. January 1999 (has links)
No description available.
1497

Physical properties of hydrated saccharides and saccharide derivatives

Derbyshire, Helen M. January 2000 (has links)
No description available.
1498

Transport in polymers : application to controlled drug release

Hyde, Thomas Miles January 1995 (has links)
No description available.
1499

The effect of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors on oxidative and hypoxic stress in the vascular endothelium

Mylankal, Kurian Joseph January 2008 (has links)
3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (statins) improve endothelial cell (EC) function by enhancing the synthesis of Nitric Oxide (NO) and attenuating the endothelial leucocyte interaction and platelet aggregation. However the effects of statins on endothelial cell proliferation, apoptosis and the mediators of these responses are not clearly defined. The aims of this research were: 1) To determine the effect of statin on EC proliferation and apoptosis. 2) To assess these cellular processes in the presence of oxidative stress and hypoxia. 3) To study the cellular response to these stresses in the presence of a statin. 4) To assess the effect of sudden withdrawal of statin on the endothelial cell proliferation and apoptosis. Statins exert a proliferative effect on EC at low concentrations and induce apoptosis at higher doses. Oxidative stress and hypoxia induce apoptosis in the EC, mediated via enhanced expression of an apoptotic protein, Bax. Statins abrogate the anti-proliferative and pro-apoptotic effects of oxidative and hypoxic stress by modulating the expression of Bax and cell cycle regulator protein Cyclin D. Acute withdrawal of statins reverses the protective effects on EC survival by promoting apoptosis and inhibiting the proliferative activity.
1500

Impurity studies of bulk drug substances by capillary electrophoresis and high performance liquid chromatography

Denk, Oliver Matthias January 2000 (has links)
No description available.

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