- About
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The Global ETD Search service is a free service for researchers
to find electronic theses and dissertations. This service is
provided by the
Networked Digital Library of Theses and Dissertations.
Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
Search results
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Investigations into the squalestatin biosynthetic gene clusterHurley, DeÌirdre January 2006 (has links)
No description available.
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Investigation of 1-deoxy-D-xylulose 5-phosphate reductoisomerase as a potential novel target for antimicrobial developmentGomez, Ana de Andres January 2006 (has links)
No description available.
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Investigation into the reactivity of pentafluorophenyl vinylsulfonate in the formation of functionalized sulfonamides of biological importanceBush, Hannah Dawn January 2005 (has links)
Sulfonamides constitute a vital and diverse class of therapeutic agents hence the development of convenient and straightforward synthetic routes to such species is a valuable endeavour. This thesis describes an exploration into the reactivity of the novel bifunctional acceptor pentafluorophenyl vinylsulfonate in the formation of biologically interesting sulfonamide species. A variety of transformations were carried out effectively at the electron-deficient olefinic portion of pentafluorophenyl vinylsulfonate to provide functionalized pentafluorophenyl esters. Subsequent displacement of the pentafluorophenyl moiety via an established aminolysis procedure then delivered the corresponding sulfonamide products. During the course of this investigation, it was established that both radical and cycloaddition routes were successful in furnishing desirable compounds. It was found that intermolecular radical addition of alkyl halides occurred readily and permitted the formation of a number of sulfonamide addition products. In addition, Diels-Alder cycloaddition with carbocyclic dienes and furan formed stable exo-bicyclic sulfonamides. Notably, 1,3-dipolar cycloaddition with a diverse library of A/-methyl-nitrones gave the corresponding isoxazolidine species with unprecedented regio- and stereoselectivity. Subsequent aminolysis delivered functionalized heterocyclic sulfonamides with potential biological importance.
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Structural studies of potential anti-microbial drug targetsNichols, Charles E. January 2004 (has links)
No description available.
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The effect of surfactant on oil uptake and erythromycin production by Saccharopolyspora erythraea CA340Tantipaibulvut, Sukon January 2004 (has links)
No description available.
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Melanization in pathogenic fungi, particularly Aspergillus fumigatus and Penicillium marneffeiYoungchim, Sirida January 2005 (has links)
No description available.
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Investigation of the effects of oligosaccharides in liquid cultures of different actinomycetesSangworachat, Nuntaka January 2006 (has links)
No description available.
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Antibiotic enhancement of toll-like receptor activation by Streptococcus pneumoniaeMoore, Lisa Jane January 2004 (has links)
No description available.
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Structural studies of Virginiamycin acetyltransferase D from Enterococcus faeciumKehoe, Laura Ellen January 2004 (has links)
No description available.
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Targeting Bacillus subtilis essential genes for the development of new antibioticsMehanni, Magda Mohamed January 2004 (has links)
No description available.
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