- About
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The Global ETD Search service is a free service for researchers
to find electronic theses and dissertations. This service is
provided by the
Networked Digital Library of Theses and Dissertations.
Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
Search results
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Issues in the design and analysis of clinical trials with time-to-event outcomesBarthel, Friederike Maria-Sophie January 2006 (has links)
Designers of clinical trials today face a number of different challenges. In a number of disease areas several treatments become available at any one time with only a limited number of patients available for investigation purposes. Furthermore, in disease areas such as HIV and cancer the pressure is high to find effective treatments quickly. Due to the recent advances in the human genome project more and more interaction effects between a treatment under study and the genetic make-up of a patient may be successfully analysed. This thesis aims to evaluate existing tools for the design and analysis of clinical trials with a time-to-event outcome and provide extensions in areas where existing tools do not perform satisfactorily. Particular emphasis is placed on sample size calculations for multi-arm and multi-stage trials and other complex mechanisms such as loss to follow-up and patient withdrawal from allocated treatment. Furthermore, advances are made in the area of treatment-covariate interactions, particularly in terms of analysis tools for such interactions.
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Random effects models to allow for clustering in individually randomised trialsLee, Katherine Jane January 2005 (has links)
No description available.
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Assessing, understanding and improving the efficiency of cluster randomised trials in primary careEldridge, Sandra Mary January 2005 (has links)
No description available.
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Selection bias in randomised controlled trials : which patient in which group?Hewitt, Catherine Elizabeth January 2006 (has links)
No description available.
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Studies on the histogenesis, differentiation and structure of spontaneous tumours in laboratory rodentsPilling, Andrew Mark January 2003 (has links)
No description available.
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Using clinical trial evidence for economic evaluation of health care interventionsMihaylova, Borislava January 2006 (has links)
No description available.
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An exploration of the representation of South Asian people in clinical trialsHussain-Gambles, Mahvash January 2004 (has links)
No description available.
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Consumer participation in the design of informed consent documentation for entry into randomised clinical trials : a cluster randomised trialGuarino, Peter David January 2005 (has links)
No description available.
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Selective reporting of outcomes in randomised trials : implications for systematic reviewsChan, An-Wen January 2003 (has links)
No description available.
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Meta-analysis to investigate methodological issues in clinical trials using pain as an exemplarBarden, Jodie January 2004 (has links)
No description available.
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