Global ETD Search

1	Trans-1,3-dithiane-1,3-dioxide as a chiral acyl anion equivalent and application in the synthesis of (R)-(-)-salbutamol Zamora, Blanca N. Esquivel January 2004 (has links) No description available. 615.72
2	Regulation of human lung mast cells by long-acting Î²â‚‚-adrenoceptor agonists Scola, Anne-Marie January 2004 (has links) No description available. 615.72
3	Regulatory roles of cAMP-specific phosphodiesterase type 4 enzymes in human pulmonary smooth muscle cells Growcott, Ellena Jacqueline January 2006 (has links) No description available. 615.72
4	Thioredoxin and the inflammatory response Callister, Matthew Eric James January 2004 (has links) No description available. 615.72
5	The regulation of airway epithelial function by adenosine and related nucleotides Burn, Mellisa January 2005 (has links) No description available. 615.72
6	Regulation of mucin secretion from airway epithelia by proteases and tachykinins Gunnell, Andrea January 2004 (has links) No description available. 615.72
7	Synthetic routes to phosphodiesterase inhibitors for the treatment of respiratory disease (Oncorhynchus mykiss, Walbaum) Johnston, Karen Anne January 2005 (has links) No description available. 615.72
8	The effect of hygroscopicity on the delivery of salbutamol salts to the lung Thompson, James Anthony January 2005 (has links) No description available. 615.72
9	Assessing asthma in adult clinical trials of inhaled B2-agonists : a search for a standard primary outcome measure Dennis, Sarah M. January 2002 (has links) Since the late 1960s the safety of inhaled B2-agonists has been questioned and the longtenn regular use of these drugs has been linked to increasing morbidity and mortality. National and international guidelines recommend that short acting inhaled B2-agonists should only be used on an "as needed" basis and yet the evidence for these recommendations is still unclear, one reason being the lack of common definition for an outcome. The Regular Use of Salbutamol Trial (TRUST) was designed to assess the risks and benefits of regular versus as needed salbutamol in mild to moderate asthma. In order to establish whether a common primary outcome measure could improve the comparability and interpretation of different trials, a systematic rcyiew of randomised controlled trials of long and short acting inhaled B2-agonists in asthmatic subjects was undertaken to identify well designed trials in this field and primary outcome measures used. The systematic review identified five different primary outcome measures from 26 trials of long and short acting inhaled B2-agonists. The TRUST definition of exacerbation was compared with the five primary outcome measures identified using the TRUST diary card data. In addition, the diary card variables (changes in PEF, symptom scores and medication use) were examined to determine the extent to which they predicted exacerbations according to the different definitions. The use of additional corticosteroids and an increase in daytime symptoms of two or more above baseline were the strongest predictors of all four definitions of exacerbation. A fall in morning PEF of 100 lImin was strongly associated with all definitions of exacerbation but was not a sensitive measure. In conclusion, exacerbations of asthma could be identified by use of additional corticosteroids and an increase in two or more of daytime symptoms. The specificity could be improved by including morning PEF but this may reduce patient compliance with study protocol in asthma trials. 615.72 Medicine
10	The effect of theophylline on the respiratory and quadriceps femoris muscles in man / Conor Jane Biophy. Brophy, Conor Jane. January 1992 (has links) Bibliography: leaves 315-366. / 368 leaves : / Title page, contents and abstract only. The complete thesis in print form is available from the University Library. / Assesses the action of dimethylxanthines on the contractility of respriatory and quadriceps femoris muscle in normal subjects and in patients at risk of respiratory muscle fatigue, using accepted techniques. / Thesis (M.D.)--University of Adelaide, Faculty of Medicine, 1992 615.72 20 Theophylline Pharmacokinetics. Reflexes Effect of drugs on. Respiratory muscles Contraction. Respiratory muscles Effect of drugs on. Drugs Physiological effect.

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