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Lymphocytic 5'-ectonucleotidase : a marker of psychological stress-induced immune suppression / Jane Blake-Mortimer.Blake-Mortimer, Jane Suzanne January 1996 (has links)
Addendum inserted (leaf 170 verso) / Some illustrations are on unnumbered leaves. / Bibliography: leaves 151-170. / xiv, 170, [25] leaves : ill. (some col.) ; 30 cm. / Title page, contents and abstract only. The complete thesis in print form is available from the University Library. / Lymphocyte 5'-ectonucleotidase (NT) was selected as a mechanism to explain the phenomenon of stress-induced immunosuppression. The findings indicates that NT is a good marker of stress induced immune suppression and correlates negatively with depression scores such as the Beck Depression Inventory, and psychological distress as measured by the TMD scores, and STAI-trait. The suppression of NT appears to be mediated by reactive oxygen species (ROS), and is consistent with the finding of normal NT levels in melancholic patients with high antioxidant intake, the heightened inflammatory responses, the low levels of zinc, the low ascorbate stores, and the down regulation of glucocorticoid receptors reported to occur in stress/depressed patients. / Thesis (Ph.D.)--University of Adelaide, Dept. of Psychology, 1997?
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Transcriptional regulation of the GM-CSF gene in T lymphocytes / Cameron Stuart Osborne.Osborne, Cameron Stuart January 1996 (has links)
Addendum pasted on front end papers. / Includes bibliographies. / 109, [99] leaves, [5] leaves of plates : ill. ; 30 cm. / Title page, contents and abstract only. The complete thesis in print form is available from the University Library. / Describes the investigation as to whether the mouse granulocyte-macrophage colony-stimulating factor and interleukin-3 genes are regulated in a similar manner as those of the human, focussing on regulation through an enhancer. / Thesis (Ph.D.)--University of Adelaide, Dept. of Microbiology and Immunology, 1996
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