Copies of author's previously published works inserted. / Bibliography: leaves 219-244. / xv, 244 leaves : ill. ; 30 cm. / Title page, contents and abstract only. The complete thesis in print form is available from the University Library. / Examines the mechanisms of induction of nitrate tolerance utilizing an in vitro model (isolated bovine coronary artery rings) and an in vivo haemodynamic model (systemic haemodynamics in patients undergoing cardiac catheterization). / Thesis (Ph.D.)--University of Adelaide, Dept. of Medicine, 1996