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Reviewing the evidence on complementary therapies : with special reference to anxiety and depressionPilkington, Karen Elizabeth January 2007 (has links)
No description available.
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Sex differences in the actions of psychoactive agents and progesterone on anxiety-related behaviour in the Mongolian gerbil (Meriones unguiculatus), and the effects of corticosterone on the hippocampal morphology of Wistar rats (Rattus norvegicus)Bridges, Nikola Jane January 2006 (has links)
Many anxiety and stress-related disorders exhibit definitive sex differences in their prevalence, symptomology, response to treatment and prognosis. Animal studies have increased the understanding of these disorders, but much of the current research in this area has been conducted using only male rats or mice. Thus, the investigation of sex differences, especially within other rodent species is still relatively ignored. There is much evidence to implicate the involvement of steroid hormones in the response to anxiety and stress. The neuroactive steroid progesterone has been associated with the regulation of anxiety behaviour in rodents, whilst the steroid corticosterone has been related to the damaging effects of stress, especially within the hippocampus. However, current investigations have failed to examine the influence of gender on these findings. The initial aim of this thesis was to evaluate the suitability of the elevated plus-maze and black-white box tests of anxiety for male and female Mongolian gerbils. The second part of this thesis then evaluates the behavioural effects of progesterone treatment and withdrawal in this species. Finally, this thesis evaluates the influence of chronic corticosterone treatment on hippocampal volume and astrocyte cell numbers in male and female rats. Pharmacological validation of the elevated plus-maze and blackwhite box revealed that diazepam produced similar anxiolysis in male and female gerbils. Buspirone appeared to modulate motor activity rather that anxiety-specific behaviours in both sexes, but to a greater extent in males. Caffeine administration induced anxiety in both tests, but was more prominent in male gerbils. FG7142 also demonstrated some anxiogenic activity, however, this increase in anxiety was represented by different behavioural alterations in each sex. Investigation of the behavioural effects of progesterone treatment revealed that acute and chronic administration produced only weak effects on anxiety-related behaviour. Even so, acute progesterone appeared to produce greater anxiolysis in females, whereas these sex differences in treatment response were abolished by chronic treatment. Withdrawal of chronic progesterone appeared to increase anxiety in both the elevated plus-maze and black-white box, and was comparable for males and females. Examination of the effects of chronic corticosterone in rats revealed no significant alteration in the volume of the hippocampus in either sex, although male rats had larger hippocampal volume than females. Prolonged corticosterone treatment did produce increases in hippocampal astrocyte numbers in specific hippocampal regions. The findings of these investigations are discussed in relation to the aetiology of anxiety disorders and stress-related hippocampal damage.
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The contribution of mindfulness to the understanding and management of distress in psychosis and the validation of the Mindfulness QuestionnaireThomas, Emily January 2005 (has links)
No description available.
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The impact of self-focused attention on social anxietySpence, Kiran January 2005 (has links)
No description available.
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The application of mindfulness to anxiety : an exploration of the effectiveness of using mindfulness based interventions in treating patients with anxietyOzcelik, Kerry January 2007 (has links)
No description available.
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A controlled comparative investigation of large group therapy for generalised anxiety disorder - "stress control"White, James David January 1989 (has links)
One hundred and nine generalised anxiety disorder (GAD) patients, referred by their General Practitioners to a clinical psychology primary care service, were assigned to either Cognitive, Behavioural, Cognitive-behavioural, Placebo or Waiting List conditions. `Stress Control' large group therapy combined didactic therapy with a workshop model and emphasised the aim of turning patients into their own `therapists' in order to enable them to deal with present and future problems. Patients were thus encouraged to view Stress Control as an `evening class' rather than `group therapy'. Measures of treatment process and outcome were obtained mainly from self-report instruments. Follow-up data were collected at six months post-treatment. At post-therapy, all active therapy conditions and, against expectation, the Placebo condition had shown significant time within treatment group change. The active therapy conditions, and to a lesser extent, the Placebo condition, were significantly different to the Waiting List condition, which, overall showed no evidence of improvement. At follow-up the active therapy condition generally enhanced therapy gains while the placebo condition maintained therapy gains. Process measures did not, with the exception of self-statement change, differentiate between the groups. Noted variable response in the main analyses was somewhat explained by various sub-group analyses. There appeared to be little benefit in dividing patients into those who experienced panic and those who did not. There was some evidence that `matching' patients to therapy, i.e. cognitive responders to cognitive therapy was of value at post-therapy although differences generally disappeared at follow-up. Synchronous change was associated with enhanced performance. Finally, attempts to predict response to Stress Control by a comparison of responders and non-responders were attempted and the results assessed in terms of clinical as opposed to statistical significance. The results of the present study are discussed with reference to other treatment outcome studies and an attempt to produce a model to account for the similar effects found across treatment conditions. The implications of these findings and some suggestions for future research for GAD and other diagnostic categories are discussed.
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