- About
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The Global ETD Search service is a free service for researchers
to find electronic theses and dissertations. This service is
provided by the
Networked Digital Library of Theses and Dissertations.
Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
Search results
Showing 1 to 10 of 21 (0.03 seconds)| 1 |
Molecular evaluation of radiosensitivity in bladder cancerLyrakos, Nikolaos January 2004 (has links)
No description available.
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Clinical and molecular prognostic factors in superficial bladder cancerBhardwa, Jeetesh Maganlal January 2008 (has links)
Aim: To identify molecular clinical and molecular prognostic indicators markers for superficial bladder cancer. Univariate statistical analysis of the clinical database revealed grade (p<0.001, Log rank test) and positive urine cytology at presentation (p= 0.002 Log rank test) are highly significant for recurrence and progression.
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Isolation and characterisation of a novel gene involved in urothelial tissue integrity and cell adhesionHailes, Fiona January 2003 (has links)
No description available.
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Growth and survival of normal and paramalignant human urothelial cellsMacLaine, Nicola J. January 2005 (has links)
No description available.
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The role of epidermal growth factor inhibitors on bladder cancer growth and invasionLazarowicz, Henry Peter January 2007 (has links)
No description available.
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Physical and functional mapping of a candidate tumour suppressor region on the short arm of chromosome 8 in bladder cancerAdams, Jacqueline January 2003 (has links)
No description available.
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Molecular epidemiology of DNA damage response to double strand breaks in bladder cancerChoudhury, Ananya January 2008 (has links)
No description available.
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Proteomic-based approaches to the identification of bladder tumour markersMunro, Nicholas Pitt January 2006 (has links)
No description available.
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Surrogate markers in transitional cell carcinoma of bladderMcKnight, J. J. January 2004 (has links)
No description available.
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Plasma protein profiling for bladder cancer biomarker discovery using UPLC-HDMS^E label-free quantitationHakimi, Amirmansoor January 2013 (has links)
In the UK, bladder cancer is the 4th most common cancer in men and 11th most common in women. In 2010, just over 10,000 new cases were diagnosed and 4,900 deaths were recorded. At their first diagnosis, the majority of bladder cancer patients (75-85%) present with non-muscle invasive disease. In 50-70% of these patients the tumour will recur and in 10-20% of them it will progress to muscle invasive disease. Mass spectrometry based proteomics has been chosen for clinical biomarker discovery due to its ability to perform qualitative and quantitative protein profiling on clinical samples. In total 90 plasma samples were used in this study in two groups of disease and control. An optimised and evaluated UPLC-IMS-DIA-MS<sup>E</sup> label-free quantitation method was used for plasma protein profiling. To our knowledge, this is the first report investigating the biomarkers of bladder cancer incorporating label-free quantitation and UPLC-IMS-DIA-MS<sup>E</sup> methodology. To assess expression level of proteins of samples in different groups a plan consisting of four data processing packages was used. Each of the packages uses different statistical means by which to identify proteins and/or compare expression levels alteration. Optimisation of the methodology helped in the thorough investigation of the plasma proteome with coverage of up to five orders of magnitude of plasma protein concentration dynamic range. In total, 11 proteins were found as possible markers of diagnosis for bladder cancer. Four of these candidates (afamin, alpha 1-B-glycoprotein, apolipoprotein-A1 and haptoglobin) were previously reported to be urinary markers of bladder cancer. CRP was overexpressed when plasma samples from patients with low grade-Ta tumours were compared to every other sample and may be used as a diagnostic marker. Similarly, afamin and haptoglobin were overexpressed in plasma samples from patients with high grade-high stage tumours when compared to samples from patients with high grade-low stage disease.
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