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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
71

Femoral impaction grafting : using bone graft substitutes

Dattani, Rupen January 2008 (has links)
Background: Femoral impaction allografting to reconstitute bone loss during revision hip surgery has shown excellent results. However, limitations with the use of allografts have warranted research to investigate if bone graft substitutes could be a suitable alternative to replace or augment allograft in impaction grafting.;Aims and Methods: The objectives of this thesis were to assess if: The use of hydroxyapatite (HA) in various combinations with allograft will be biologically effective and functionally stable using a cemented impaction grafting technique in an ovine hemiarthroplasty model. The different treatment groups were compared by measuring the ground reaction forces and new bone formation. The addition of mesenchymal stem cells (MSCs) to allograft, HA or an allograft:HA mixture enhances the amount of new bone formation compared with impaction of the scaffold alone in an ovine metaphyseal femoral bone defect model. The architecture of the HA scaffold influences bone formation in an extra-skeletal sheep model.;Results: HA: allograft mixture of up to 90:10 demonstrated similar functional stability and amount of new bone formation as a 50:50 mixture. Addition of MSCs to allograft or a 50:50 allograft:HA mixture enhances the amount of new bone formation compared with unimpacted constructs. HA either alone or combined with MSCs induces bone growth only when constructed in block form and not in identical porous granular form.;Conclusion: HA is a suitable bone substitute to augment allograft and may be replace bone graft completely in impaction grafting of a femoral component. This has important clinical implications as HA is readily available, easy to use in surgery and not associated with the adverse effects encountered with allografts. The use of MSCs in the treatment of osteolysis holds great potential but further work is required to assess if this technology is transferable to humans.
72

A new modified injectable brushite-based calcium phosphate bone cement

Saadalla, Marco Edward January 2006 (has links)
No description available.
73

Cellular responses in rotator cuff tears

Matthews, Timothy January 2008 (has links)
No description available.
74

The impregnation of medical silicone elastomers and acrylic bone cements with antimicrobial drugs

Bayston, R. January 1980 (has links)
No description available.
75

Neutrophil activation in organ failure after thoraco-abdominal aortic aneurysm repair

Foulds, Sharmila January 1999 (has links)
No description available.
76

Renal allograft rejection : in situ studies of tubulitis

Robertson, Helen January 2002 (has links)
No description available.
77

The effect of donor lung injury on outcome after human lung transplantation

Fisher, Andrew John January 2001 (has links)
No description available.
78

The impact of coronary bypass surgery on myocardial perfusion and function

Woldman, Simon January 2002 (has links)
No description available.
79

Vessel and aneurysm reconstruction using speed and flow coherence information in phase contrast magnetic resonance angiograms

Chung, Chi Shing January 2001 (has links)
No description available.
80

Refinement Of Colorectal Referrals Using A Patient Consultation Questionnaire And Weighted Numerical Score

Hodder, Rupert J. January 2006 (has links)
No description available.

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