Name of the thesis Effect of nitric oxide on cerebral blood flow during neuronal activity Aim of the thesis The aim of this thesis is to determine whether the application of 7-nitroindazole, relatively specific inhibitor of neuronal nitric oxide synthase, affects the baseline blood pressure. Furthermore, to determine whether the application of the substance affects the baseline cerebral blood flow and whether it influences blood flow in brain during transcallosal stimulation with increasing frequency. Research method The research took place at the premises of the Institute of Physiology, Academy of Sciences of the Czech Republic. Experiments were carried out on laboratory albino Wistar rats. The group contained both experimental and control sample. General anesthesia was performed to rats, stimulating and sensing electrodes were implanted in epidural area of sensorimotor cortex and Laser Doppler flow probe was implanted into the contralateral hemisphere. A plastic catheter was applied in the carotid artery for measuring systemic blood pressure. In the first part of the experiment, we tested the effects of 7-nitroindazole on the systemic blood pressure. In the second part of the experiment, we investigated the effects of 7-nitroindazole on baseline cerebral blood flow. The third part of the...

M.Com. / The proliferation of computers and the advances in technology introduced a number of new and additional management and control considerations. The inherent complexity of these environments has also increased the need to evaluate the adequacy of controls from an audit perspective. Due to the increasing use of database management systems as the backbone of information processing applications and the inherent complexities and diversity of these environments, the auditor is faced with the challenge of whether and to what extent reliance may be placed on the data contained in these databases...

M.A. / We live in a world, that is basically spiritually and morally bankrupt. The tidal wave of crime and thorny issues like aids and abortion, are only some of the consequences of this moral decay. Even the Church has not been able to avoid this decay and the very high divorce rate amongst Christians is proof of this moral regression. Pastoral counsellors are often stunned and amazed by the immorality that oftentimes occurs in Christian circles. Is there an answer? The ethical guidelines as found in the Sermon on the Mount, offers a solution. Can ethical guidelines, pronounced 2000 years ago, offer any solutions in this post-modern century? Are these not outdated norms, applicable in an ancient milieu, offering no solution for today? Can it still have any hermeneutical value? These are the questions addressed in this research. The ethical guidelines, as offered by the Sermon on the Mount, can be approached in two different ways. It can be viewed as an outdated ancient principle, with no normative value in a post-modern century, or as a guideline that withstood the test of time and still counts as the will of God, for every believer in his ethos. To maintain standards at the centre of God’s will, is an exalted ideal for every believer that earnestly views his Christianity. The ethical guidelines in the Sermon on the Mount, puts the standards of God in a practical manner, but in such a way that it brings every Christian to the realisation of his incapacity, to live it in practice. The result of this study has shown that the living of the Sermon on the Mount (especially the figurative language components contained in it) in a Christian ethos, is not a utopian dream, but relevant guidelines, that with the assistance of the residing Holy Spirit, can be lived as normative ethical principles in a Christian ethos.

Thesis advisor: Robert Murphy / A study of recent inflation dynamics in the G-7, this paper discusses a problem with the Phillips curve which arose during the Great Recession (2008-2011). We find that work with time-varying slope, expectation anchoring, and core inflation can correct for the under-predictions that develop in the Phillips Curve during the recession, improving its accuracy throughout the G-7. / Thesis (BA) — Boston College, 2012. / Submitted to: Boston College. College of Arts and Sciences. / Discipline: Economics Honors Program. / Discipline: Economics.

Le transcodage est un élément clé dans la transmission vidéo permettant à une séquence vidéo de passer d'un type de codage à un autre afin de s'adapter au mieux aux capacités de transport d'un canal de transmission. L'intérêt de ce type de traitement est de faire profiter un maximum d'utilisateurs possédant des terminaux variés dont la résolution spatiale, la résolution temporelle affichable, et le type de canal utilisé pour accéder au média varient fortement, et cela à partir d'une seule source de qualité et résolution maximale, stockée sur un serveur, par exemple. Le transcodage est adapté dans les cas où l'on souhaite envoyer une séquence vidéo vers un destinataire et dont le chemin serait constitué de divers canaux de transmission. Nous avons réalisé un transcodeur par requantification ainsi qu'un transcodeur par troncature. Ces deux méthodes ont été comparées et il apparait qu'en termes de qualité d'image l'une ou l'autre de ces méthodes est plus efficace selon le contexte. La suite de nos travaux consiste en l'étude du standard scalable dérivé de H.264 AVC, le standard SVC (Scalable Video Coding). Nous avons souhaité étudier un transcodeur en qualité, mais aussi en résolution spatiale qui permettra de réécrire le flux SVC en un flux AVC décodable par les décodeurs du marché actuel. Cette transposition est réalisée grâce à une architecture reconfigurable permettant de s'adapter aux nombreux types de flux pouvant être conformes au standard SVC d' H.264. L'étude proposée a aboutie à une implémentation partielle d'un transcodeur du type SVC vers AVC. Nous proposons dans cette thèse une description des implémentations de transcodage concernant les formats AVC puis SVC / Transcoding is a key element in the video transmission allows a video to go from one encoding type to another in order to adapt better to the transport capacity of a transmission channel. The advantage of this type of treatment is to make the most of users with various terminals with spatial resolution, temporal resolution displayable, and type of channel used to access the media vary widely, and from that of a single source of quality and maximum resolution, stored on a server, for example. Transcoding is appropriate where you want to send a video to a recipient and whose path would consist of various transmission channels. We realized by a transcoder and a requantization transcoder by truncation. These two methods were compared and it appears that in terms of image quality in either of these methods is more effective depending on the context. Following our work is the study of the standard H.264 AVC scalable derivative of the standard SVC (Scalable Video Coding). We wanted to study as a transcoder, but also in spatial resolution which will rewrite the SVC flow in a stream stroke decodable by decoders on the market today. This mapping is achieved through are configurable architecture to adapt to many types of flow which may conform to standard SVC to H.264. The proposed study has accomplished a partial implementation of a transcoder type SVC to AVC. We propose here a description of the implementations on AVC transcoding and SVC

The expression of CCR7 was evaluated in different cancer cell lines by using flow cytometry, western blot, Immunofluorescence and immunohistochemistry. We showed for the selected cell lines that the expression is maintained in cells grown as spheroids, and xenoplanted in mice. Furthermore, we showed the expression of CCR7 correlates with stage of the disease in patient derived head and neck cancer tissue. We also showed that expression of CCR7 in cancer cell lines correlates with migratory aptitude towards CCL21 in a scratch assay, Boyden chamber assay and spheroid invasion assay. We then showed that the expression of CCR7 is elevated under serum starvation and under hypoxia in cancer cell lines grown as monolayers and as spheroids; and that there is a correlation between hypoxia and CCR7 expression in spheroids, xenografted cells and clinical cancer tissue. However, we found that in cell line OSC-19, the increase in the expression of CCR7 did not correlate to increased migration. Our investigations following this observation showed that whilst hypoxia increases the expression of CCR7, it concurrently causes a decrease in reactive oxygen species (ROS) which strongly abrogates migratory aptitude in OSC-19, resulting in an overall loss of migration in OSC-19 cells. In addition, we characterised OSC-19 as a suitable model to evaluate small molecule CCR7 antagonists using a number of different assays. In particular, we showed that ICT13069 antagonised response of this cell line across a number of drivers of malignancy such as migration, invasion in 2D and 3D models.

Ce travail est à la jonction de deux domaines de recherche que sont la turbulence et le traitement d'image. L'objectif principal est de proposer de nouvelles méthodologies pour reconstruire les petites échelles de la turbulence à partir de mesures grande échelle. Une des contributions de ce travail est de revisiter des méthodes conventionnelles et de proposer de nouveaux modèles basés sur les travaux récents en traitement d’image pour les adapter à une problématique de turbulence. Le premier problème consiste à trouver une fonction de correspondance empirique entre les grandes et les petites échelles, une approche classique pour les modèles de type regression. Nous introduisons également une nouvelle méthode appelée “apprentissage de dictionnaire” pour laquelle une représentation couplée des grandes et des petites échelles est déduite par apprentissage statistique. Le deuxième problème est de reconstruire les informations à petites échelles par fusion de plusieurs mesures complémentaires. Le modèle de type “propagation de la moyenne non-locale” exploite la similarité des structures de l'écoulement alors que les modèles bayesiens de fusion proposent d'estimer le champ le plus probable en fonction d'informations données, on parle d’estimateur maximum a posteriori. Toutes les méthodes sont comparées et validées sur des bases de données numériques pour lesquelles les informations sont disponibles à toutes les échelles. Les performances des différentes approches sont analysées pour chacune des configurations. Ces résultats peuvent être utilisés dans une approche de type co-conception où il s’agit d'imaginer différents dispositifs expérimentaux définis conjointement avec les traitements numériques prévus pour extraire l’information utile. Les résultats de nos analyses peuvent être utilisés pour définir de nouvelles expériences qui maximisent la qualité des informations obtenues après traitement. / This work lies in between the research domains of turbulence and image processing. The main objectives are to propose new methodologies to reconstruct small-scale turbulence from measurements at large-scale only. One contribution of this work is a review of existing methods. We also propose new models inspired from recent works in image processing to adapt them to the context of turbulence. We address two different problems. The first problem is to find an empirical mapping function between large and small scales for which regression models are a common approach. We also introduce the use of “dictionary learning” to this problem of turbulence. The idea is to train coupled representations of large and small scales for reconstruction. The second problem is to reconstruct small-scale information via fusion of complementary measurements. The non-local means propagation model exploits the similarity of structures in the flow, while the Bayesian fusion model estimates the most probable fields given the measurements thanks to a maximum a posteriori estimate. All methods are validated and compared using numerical databases where fully resolved velocity fields are available. Performances of the proposed approaches are also characterized for various configurations. These results can be considered under the co-conception design framework, where different experimental setups are designed with respect to their corresponding post-processing. Our detailed analyses can be used to design new experiments that maximize the level of useful information after processing measurements.

The focus of this thesis is on the acquisition of major capital equipment within Australia's defence system. For the purposes of this analysis, major capital equipment constitute selected projects with a total value of at least $200 million. The projects selected for examination are from each of the three arms of the military service. These projects are: the Royal Australian Air Force's BLACKHAWK helicopters, the Army's PERENTIE vehicles, and the Royal Australian Navy's Australian FFG-7 FRIGATES. These projects were chosen because they share similar planning and management related characteristics. They represent substantial public sector investments. The technology used in each of the systems is available 'off-the-shelf but the way in which the systems were ultimately assembled and produced are uniquely Australian: this adaptation and local innovation involved developmental work. Since each of these projects is almost complete, a comprehensive analysis of the project has been possible. The study of these particular projects provides the basis for a comparative analysis of the acquisition of major defence projects, and facilitates the development of project planning and management 'lessons'. Since current Australian public (and private) sector policies seek to maximise the use of leading edge technology by adapting it to meet specific local requirements; the examination of these three projects provides an objective determination of the validity of such policies.

Bibliography: p. 331-340. / x, 340 p. : ill. ; 30 cm. / Title page, contents and abstract only. The complete thesis in print form is available from the University Library. / Using sensory ranking, studies aroma variability of a chardonnay and a cabernet sauvignon matured in new oak barrels. Oak wood-derived volatile compounds are analysed using gas chromatography, to suggest which natural and cultural variables are involved in each aroma variation. / Thesis (Ph.D.)--University of Adelaide, Dept. of Horticulture, Viticulture and Oenology, 1998

<p>Performance is the driving force for the effective network utilization in the current telecommunication world. The thesis aims to define suitable performance measurement methodologies for communication over stack based Signalling System No 7 (SS7). This thesis also throws a quick glance on open source SS7 and Ericsson proprietary SS7 protocols, to devise performance measurement approach that can be adopted to develop sophisticated tools. We adopt a scientific experimental approach for numerical measurement of throughput and latency of the protocol stack. Our current work finishes experimentation with open source SS7 protocol (SCTP) in Fedora based two identical servers. SCTP (Stream Control Transmission Protocol) is an important transport layer protocol for communication of SS7 message over an IP network. Message communication using SCTP protocol over an IP/Ethernet network between these two identical servers has been measured and analyzed using the IPerf tool. TCP (Transmission Control Protocol) being another important transport layer protocol of TCP/IP stack, the performance of TCP is compared with SCTP. The results prove that under normal circumstances TCP gains over SCTP and our analysis support that under multi homing support, SCTP should gain over TCP when throughput is measured</p>