Diss. (sammanfattning) Uppsala : Uppsala universitet, 2006. / Härtill 4 uppsatser.

Thesis (doctoral)--Katholieke Universiteit te Nijmegen.

Thesis (M.S.) -- University of Tennessee, Knoxville, 2006. / Title from title page screen (viewed on Sept. 20, 2006). Thesis advisor: E. Grady Bouge. Vita. Includes bibliographical references.

Proefschrift Maastricht. / Met lit. opg. - Met samenvatting in het Nederlands.

Proefschrift Universiteit Maastricht. / Met bibliogr., lit. opg. - Met samenvatting in het Nederlands.

Made available in DSpace on 2014-10-09T12:31:56Z (GMT). No. of bitstreams: 0 / Made available in DSpace on 2014-10-09T13:56:15Z (GMT). No. of bitstreams: 1 11271.pdf: 1620413 bytes, checksum: 0e0a644effc3d9a058cc124ef5850408 (MD5) / Dissertacao (Mestrado) / IPEN/D / Instituto de Pesquisas Energeticas e Nucleares - IPEN-CNEN/SP

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AN ABSTRACT OF THE THESIS OF Sarah Sheffer, for the Master of Science degree in Food and Nutrition, presented on September 3, 2009, at Southern Illinois University Carbondale. TITLE: "R. U. A. HEALTHY KID?"- NON-INVASIVE SCREENING FOR RISK FACTORS FOR TYPE 2 DIABETES AT VIENNA GRADE SCHOOL MAJOR PROFESSOR: Dr. Sharon Peterson It is estimated that 1 in 3 children born after the year 2000 will develop some form of diabetes (CDC, 2007). Through Public Act 92-0703, the state of Illinois has started requiring screening for T2DM at the 6th and 9th grade school physicals following the ADA guidelines (IDHS, 2006). The ADA recommends screening children ten and older with a BMI ≥ 85th percentile for two additional risk factors for T2DM (ethnic minority, positive family history of T2DM, hypertension, acanthosis nigricans) (ADA, 2000). While much research has been done, few studies in the U.S. have looked at traditionally "low risk" populations (Sinha 2002, Whitaker 2004, Arslanian 2005). Our study sought to further understand the prevalence of risk factors in a predominantly Caucasian elementary school (K-8 grade). Our study (N=299) found approximately 67% of students to have 1 or more risk factors for T2DM and classified 17 students "at risk" for T2DM. Following Illinois Public Act 92-0703, only 1 student would have been identified "at risk" for T2DM. When comparing "at risk" status, all risk factors except ethnicity were found statistically significant (p< 0.001). Hypertensive "at risk" students were more likely to be morbidly obese (p< 0.001). Our study also found more risk factors as BMI increased.

Made available in DSpace on 2014-06-11T19:27:15Z (GMT). No. of bitstreams: 0 Previous issue date: 2010-07-02Bitstream added on 2014-06-13T19:14:30Z : No. of bitstreams: 1 rino_as_me_botfmvz.pdf: 1140459 bytes, checksum: 5597016d559daa886389f4ed9c58c88b (MD5) / Universidade Estadual Paulista (UNESP) / As fibras musculares esqueléticas são entidades versáteis, capazes de alterar seus fenótipos de acordo com a demanda energética. Para avaliar os efeitos do exercício de enduro no músculo esquelético, foram utilizados neste estudo 36 equinos da raça Puro Sangue Árabe divididos em dois grupos: treinados e não treinados para enduro. Foram obtidos fragmentos musculares da região profunda do músculo glúteo médio e processados para técnicas histoquímicas e imunoistoquímica, utilizando-se anticorpos específicos contra isoformas de cadeia pesada de miosina (MyHC) lenta e rápida. As fibras identificadas pela histoquímica e imunoistoquímica foram analisadas uma a uma. Determinou-se a porcentagem dos diferentes tipos de fibras musculares, e avaliou-se que, a porcentagem das fibras do tipo IIA foi significativamente mais alta do que a porcentagem das fibras dos tipos I e IIX no grupo não treinado (P<0,05). Em contra partida, a porcentagem das fibras do tipo I foi significativamente mais alta do que a porcentagem das fibras dos tipo IIA e IIX no grupo treinado (P<0,05). Também foram analisados, a média da área de corte transversal e o menor diâmetro da fibra e observou-se que, a média de corte transversal das fibras do tipo IIX foi significativamente maior comparada à média de corte de transversal das fibras dos tipos I e IIA em ambos os grupos. Em conclusão pode-se afirmar que, o exercício de enduro em equinos aumenta a população das fibras de contração lenta, em detrimento da população de fibras de contração rápida / The skeletal muscle fibers are versatile entities capable to change their phonotype according to energy demand. To evaluate the effects of exercise over equine skeletal muscle in this study, 36 Arabian horses divided in 2 groups trained and untrained for endurance were used. The samples was obtained from de deep region of the gluteus medius muscle and processed for histochemistry and immunohistochemistry using specific monoclonal antibodies to selected fast and slow isoforms myosin heavy chain (MyHC). The histochemical and immunohistochemical categorization of the muscle fiber types were compared fiber by fiber. It was analyzed the percentage of different fiber types where, in the untrained group, the percentage of the fiber type IIA was higher significantly than the percentage of fiber types I and IIX (P<0.05). Unlike, the group trained showed a higher proportion of fiber type I than the fiber type IIX (P<0.05). The cross section area and lesser fiber diameter were also analyzed, and showed that, CSA of fiber type IIX was higher significantly than fibers I and IIA (P<0.05) in both groups. In conclusion, endurance exercise in equines increase the population of slow-twitch fibers in detriment of fast-twitch fibers

Made available in DSpace on 2014-10-09T12:37:03Z (GMT). No. of bitstreams: 0 / Made available in DSpace on 2014-10-09T13:56:36Z (GMT). No. of bitstreams: 1 04490.pdf: 6751452 bytes, checksum: b98c1dc1b829918d01b97249140225c3 (MD5) / Dissertacao (Mestrado) / IPEN/D / Instituto de Pesquisas Energeticas e Nucleares - IPEN/CNEN-SP