In this work, the feasibility to perform substructuring technique with experimental data is demonstrated. This investigation examines two structures with different additional mass‑loads, i.e. transmission simulators (TSs). The two structures are a single blade and the hub together with two blades from an Ampair 600 wind turbine. Simulation data from finite element models of the TSs are numerically decoupled from each of the two structures. The resulting two structures are coupled to each other. The calculations are made exclusively in the frequency domain. A comparison between the predicted behavior from this assembled structure and measurements on the full hub with all three blades is carried out. The result is discouraging for the implemented method. It shows major problems, even though the measurements were performed in a laboratory environment.