Recent accomplishments in link-level and radio technologies have significantly improved the performance of wireless links. Wireless mobile ad hoc networks, however, typically only take limited advantage of these enhancements. In this research, the medium access control protocol and ad hoc routing protocol are extended to take advantage of radios offering multi-user interference cancellation and direct-sequence spread-spectrum functionality, by encouraging multiple simultaneous connections and adaptively changing communication parameters on a per-packet basis. Through its environment characterization techniques, the adaptive direct sequence spread spectrum MAC protocol for non-broadcast multiple access networks (ADIM-NB) improves several aspects of the wireless mobile ad hoc network performance, including throughput, delay, stability, and power consumption, through its use of spread-spectrum multiple access and four different adaptive algorithms. The four adaptive algorithms change processing gain, forward error correction coding rate, transmit power, and number of simultaneous connections. In addition, the ad hoc routing protocol is extended with the clustering algorithm for mobile ad hoc network (CAMEN). With ADIM-NB in mind, CAMEN discourages the use of broadcast messages, supplements ADIM-NB's functionality at the network level, and improves the network scalability by aggregating nodes into clusters. Both protocols are intended to lead to more powerful and flexible communication capabilities for wireless nodes. Simulation models have been developed and simulated to verify the performance improvements of both protocols at the network-level as well as provide a means to perform trade-off analysis. Results indicate that the network capacity is increased between 50% in a moderately loaded network to 100% in a heavily loaded network over a non-adaptive MAC protocol. The delay also improve significantly in most scenarios of interest. / Ph. D.