Les accélération de faisceaux de forte puissance et le bombardement d'une cible de spallation permettent d'atteindre les flux requis pour application aux réacteurs sous-critiques pilotés par un accélérateur de particules (ADSR).Parmi les methodes d'acceleration, on trouve les accélérateurs circulaires, en particuler les FFAG et les cyclotrons. Le travail de cette these porte sur l'évaluation de ces methodes pour la production de faisceaux de protons de classe multi-mégawatts, y compris la participation à des collaborations d'études internationales de design. Une evaluation de la methode ADSR comme candidat potential pour resoudre le probleme des dechets nucleaires est finalement etablie. / High power proton accelerators allow providing, by spallation reaction, the neutron fluxes necessary in thesynthesis of fissile material, starting from Uranium 238 or Thorium 232. This is the basis of the concept ofsub-critical operation of a reactor, for energy production or nuclear waste transmutation, with the objective ofachieving cleaner, safer and more efficient process than today’s technologies allow.Designing, building and operating a proton accelerator in the 500-1000 MeV energy range, CW regime,MW power class still remains a challenge nowadays. There is a limited number of installations at presentachieving beam characteristics in that class, e.g., PSI in Villigen, 590 MeV CW beam from a cyclotron, SNS inOakland, 1 GeV pulsed beam from a linear accelerator, in addition to projects as the ESS in Europe, a 5 MWbeam from a linear accelerator.Furthermore, coupling an accelerator to a sub-critical nuclear reactor is a challenging proposition: some ofthe key issues/requirements are the design of a spallation target to withstand high power densities as well asensure the safety of the installation.These two domains are the grounds of the PhD work: the focus is on the high power ring methods inthe frame of the KURRI FFAG collaboration in Japan: upgrade of the installation towards high intensityis crucial to demonstrate the high beam power capability of FFAG. Thus, modeling of the beam dynamicsand benchmarking of different codes was undertaken to validate the simulation results. Experimental resultsrevealed some major losses that need to be understood and eventually overcome.By developing analytical models that account for the field defects, one identified major sources of imperfectionin the design of scaling FFAG that explain the important tune variations resulting in the crossing of severalbetatron resonances. A new formula is derived to compute the tunes and properties established that characterizethe effect of the field imperfections on the transverse beam dynamics. The results obtained allow to developa correction scheme to minimize the tune variations of the FFAG. This is the cornerstone of a new fixed tunenon-scaling FFAG that represents a potential candidate for high power applications.As part of the developments towards high power at the KURRI FFAG, beam dynamics studies have toaccount for space charge effects. In that framework, models have been installed in the tracking code ZGOUBIto account for the self-interaction of the particles in the accelerator. Application to the FFAG studies is shown.Finally, one focused on the ADSR concept as a candidate to solve the problem of nuclear waste. In orderto establish the accelerator requirements, one compared the performance of ADSR with other conventionalcritical reactors by means of the levelized cost of energy. A general comparison between the different acceleratortechnologies that can satisfy these requirements is finally presented.In summary, the main drawback of the ADSR technology is the high Levelized Cost Of Energy comparedto other advanced reactor concepts that do not employ an accelerator. Nowadays, this is a show-stopper forany industrial application aiming at producing energy (without dealing with the waste problem). Besides, thereactor is not intrinsically safer than critical reactor concepts, given the complexity of managing the targetinterface between the accelerator and the reactor core.