The main focus of this diploma thesis is the characteristics of key aspects, which are important when designing, implementing and maintaining web application, whereas these aspects differ according to business model of the web application. The thesis reflects modern trends in the areas of web project management, UX, web design, E-Commerce process management etc. The thesis consists of the introduction, theoretical part, practical part and conclusion. In the introduction I present the reason for picking this topic, the more in-depth targets of the thesis, preconditions, restrictions, in-depth structure, sum-up the expected contribution and present research of the field. The theoretical part consists of the information about online business and introduction of the web applications. Furthermore, the key domains are presented with the new trends in different areas of web applications. In the practical part, at the beginning, there are categories of web applications defined, which are based on different business models introduced earlier. This part is followed by the comprehensive analysis in the field of web E-Commerce applications for each category of the web application, with the output of trends and best practices in the field according to each domain of the web application. It is then followed by the analysis of situation around web applications in general, because here were also some trends and best practice noticed. In conclusion I sum up the acquired results, introduce the contribution of the thesis and think about the situation around the web applications.