Korsakoff's syndrome (KS) is characterized by the acute onset of a severe anterograde memory impairment and a less pronounced retrograde amnesia. In addition to deficits in memory, executive function, visuo-spatial abilities, and visuo-perception are impaired. The main structures involved in the neuropathology of KS are the mammillary bodies and the thalamus. It is generally assumed that KS is a stable amnesic condition, and little research has been done in studying the effects of aging on the syndrome. / A group of elderly KS patients were evaluated on a large battery of neuropsychological tests to examine general cognitive function, memory, attention, visuo-spatial ability, and executive function. Their performance was compared to age-matched Alzheimer's disease patients and healthy controls. Results showed that there is an interaction between age and KS, with exaggerated deficits seen in memory and executive function, as well as new deficits in semantic memory. / To better understand KS, the thesis provides a review focusing on human, English language studies published between the years 1995 and 2008. Updates on the current findings of treatment and prevention, genetics and prevalence, neuropathology, and neuropsychology including memory and frontal function are provided. In addition, comparison studies of KS to other neurological disorders are summarized.

No description available.

No description available.

Background: Chronic pain is a frequent and undertreated ailment within the long-term care community (Herman et al, 2009). The likelihood of experiencing pain increases with age and failure to treat this condition may expose individuals to prolonged and unnecessary suffering (Ramage-Morin, 2008). Furthermore, undertreated pain can lead to a life of inactivity and a failure to carry out normal social and vocational roles which in term may result in higher rates of depression, anxiety and sleep disorders (Clark, 2000). The present study aimed to explore staff perceptions on current pain management within long-term care including insights to future needs in optimizing pain management. This work will contribute to the overall awareness surrounding possible reasons that current pain management within long-term care is viewed as suboptimal (Herman et al, 2009). Methods: A qualitative, post-positivist grounded theory study was carried out in order to investigate staff-perceived strengths, weaknesses and barriers surrounding the topic of pain-management within the long-term care setting. Semi-structured interviews with 17 long-term care staff members from a variety of vocations were conducted with a focus on identifying and clarifying properties surrounding the notion that pain management is currently suboptimal. A focus group session was implemented as a method to further develop the emerging grounded theory. Results: Nine themes surrounding pain management within the long-term care setting were identified in the present study. These themes gave rise to the core concept of creating an environment supportive of optimal pain management. The nine themes were integrated into the theory of optimization of pain management within long-term care through thematic interpretation. The focus group session further developed and confirmed themes identified throughout the one-on-one interviews as well as expanded the discussed theory. Discussion: The developed theory of optimization of pain management within the long-term care setting provides a comprehensive overview of the current barriers facing adequate pain management as well as outlines future suggestions for improvement of managing pain within the long-term care setting.

Issues concerning gay, lesbian, bisexual, transgender and intersex (GLBTI) older people have been almost completely neglected in Australian gerontology. This is reflected in textual discourse, clinical and service practices, training and education, research approaches and policy development. The research presented in this thesis investigates whether lessons might be drawn from the experience of activists in the United States of America (USA) and then applied to Australian gerontology, with regard to the recognition of GLBTI issues. As such, the research aims to provide guideposts for a process of change in Australia, by the investigation of the factors involved in collective action. / A critical research paradigm underpinned the research approach. The research was informed by social movement theory which includes structural and cultural dimensions of collective action. The approach was also informed by the researcher's history of involvement in activism. Qualitative descriptive research, involving the triangulation of methods, was conducted in Australia and the State of California, in the USA. Fieldwork took place in three phases, involving a questionnaire mailed to Australian activists, analysis of documents held in archival collections in San Francisco and Long Beach, interviews with key activists involved in the Californian process of change and interviews with older GLBTI Australian activists. Throughout the period of the inquiry, the researcher recorded a log of relevant action that occurred in Australia. / Thesis (PhDHealthSciences)--University of South Australia, 2004.

Issues concerning gay, lesbian, bisexual, transgender and intersex (GLBTI) older people have been almost completely neglected in Australian gerontology. This is reflected in textual discourse, clinical and service practices, training and education, research approaches and policy development. The research presented in this thesis investigates whether lessons might be drawn from the experience of activists in the United States of America (USA) and then applied to Australian gerontology, with regard to the recognition of GLBTI issues. As such, the research aims to provide guideposts for a process of change in Australia, by the investigation of the factors involved in collective action. A critical research paradigm underpinned the research approach. The research was informed by social movement theory which includes structural and cultural dimensions of collective action. The approach was also informed by the researcher?s history of involvement in activism. Qualitative descriptive research, involving the triangulation of methods, was conducted in Australia and the State of California, in the USA. Fieldwork took place in three phases, involving a questionnaire mailed to Australian activists, analysis of documents held in archival collections in San Francisco and Long Beach, interviews with key activists involved in the Californian process of change and interviews with older GLBTI Australian activists. Throughout the period of the inquiry, the researcher recorded a log of relevant action that occurred in Australia. The data revealed three key findings regarding the Californian process of change and the Australian situation: Aspects of the change process in the State of California, in the USA, involving personal style, individual biography and devotion to the cause, formed a vital personal dimension of collective action; Issues associated with leadership and self-determination were of significance in shaping the change process and determining the outcome of collective action in California; Interest in GLBTI ageing issues and pockets of relevant action were evident in Australia, but a co-ordinated collective process of action was not identified. This thesis argues that lessons drawn from the process of collective action in the State of California could inform action that may take place in Australia. A dialogue between Australian activists, addressing the outcomes of this research, could also assist the development of a locally appropriate process of change. The thesis reveals implications and challenges for the aged care industry, in relation to service provision, education and training, policy development, and further research. The research provides a contribution to the discussion of matters which could assist to minimise discrimination, alleviate fear, promote equity and enhance the value of diversity in Australian gerontology in the future. / thesis (PhDHealthSciences)--University of South Australia, 2004.

Thesis (D. Min.)--Southwestern Baptist Theological Seminary, 1988. / Includes bibliographical references (leaves 112-128).

Diss. (sammanfattning) Stockholm : Karol. inst., 2002. / Härtill 6 uppsatser.

Diss. (sammanfattning) Stockholm : Karol. inst. / Härtill 5 uppsatser.

Diss. (sammanfattning) Stockholm : Karol. inst. / Härtill 5 uppsatser.