Thesis (Ph. D.)--University of Wisconsin--Madison, 1957. / Typescript. Abstracted in Dissertation abstracts, v. 17 (1957) no. 10, p. 2286. Vita. eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (leaves 60-63).

Note:

There are three primary routes by which occupational exposure to hazardous substances occurs: inhalation, dermal absorption, and ingestion. Of these, ingestion has been the least studied. Ingestion exposure is typically controlled in workplaces by the provision of clean eating areas that are separated from the work areas, and by encouraging hand-washing prior to eating. However, this control strategy does not affect ingestion exposure that can occur when contaminated hands or objects contact the mouth; these sorts of exposures can occur during work tasks in the general work area. For example, these sorts of contacts can occur when workers wipe their mouths or noses, chew pens or glasses, or bite their nails. Exposure by this pathway is called inadvertent ingestion exposure. In addition to the insertion of contaminated hands and objects directly into the oral cavity, contact can occur with the perioral area (the area surrounding the mouth) and transferred substances can subsequently transfer to the mouth. The aim of this thesis was to study inadvertent ingestion exposure in order to develop a generic predictive screening model to allow occupational hygienists and risk assessors to estimate exposure by inadvertent ingestion for a range of exposure scenarios. The thesis project was carried out in a series of steps, all of which are described below. The steps were carried out in the order presented and the findings from the work on earlier steps influenced the work carried out in later steps.

No description available.

No description available.

The study described in this thesis was designed to investigate the use of Immobilized Artificial Membrane (IAM) chromatography alone, or in combination with physiochemical descriptors, for predicting intestinal drug absorption in humans. / Thesis (MApSc(Pharmacy) )--University of South Australia, 2007.

The study described in this thesis was designed to investigate the use of Immobilized Artificial Membrane (IAM) chromatography alone, or in combination with physiochemical descriptors, for predicting intestinal drug absorption in humans.

Thesis (Ph. D.)--Johns Hopkins University, 1916. / Cover title. Vita. "Reprinted from the Journal of experimental zoölogy, vol. 21, no. 3, October, 1916." "Literature cited": p. 424.

Thesis (M.D.)--University of Pennsylvania, 1805. / Microform version available in the Readex Early American Imprints series.

The intent of this study was to compare the rate of gastric emptying of three commercially available athletic drinks (GA, BT, and BP) against water, and in doing so to assess the exchange of water, carbohydrate and electrolytes 15 minutes after ingestion. Nine men and three women reported to the laboratory after having fasted for 12 hours.' A No. 20 French Levine Tube was inserted through the nasal passage and into the stomach. The subjects drank down 400 ml of the test solution containing 25 mg of phenol red which was used as a volume indicator. Fifteen minutes after ingestion, the gastric contents were aspirated via the tube by means of a 50 ml syringe. The 4 conditions were tested in one morning, with the order of feedings rotated between subjects. The recovered gastric contents were measured for total volume, volume of original drink, carbohydrate content and gastric electrolyte exchange. Student t values were used to test the difference between means set at the P < .05 level of confidence. BT and BP were found to empty statistically the same volume of fluid in 15 minutes as did water, while GA emptied 39% less volume than did water. BT, BP, and GA contributed 1.9, 4.5 and 6.8 gm of carbohydrate respectively in 15 minutes. These data are in agreement with previous findings that high glucose concentrations (GA - 4.5 gam) cause a slowing of gastric emptying.