This study investigated the management of information and communication technologies (ICTs) at academic libraries in selected public universities in Ghana. The purpose for this study was to investigate the managerial processes and challenges in terms of conceptualization, policies, planning, implementation and strategies involved in ICTs adoption in order to formulate strategies for their management in Ghanaian academic libraries. Specifically, the objectives of the study were to review and explore the status and level of ICT diffusion in Ghanaian university; audit the procedures, processes and factors that influence ICT adoption and implementation in Ghanaian university libraries; establish the institutional policies, strategies and human resource that is in place and available for the adoption; determine the factors that hinder the adoption and management of ICTs in Ghanaian university libraries; and design a framework for effective and efficient management of ICTs in Ghanaian public university libraries. The study adopted mixed-method research design approach combining both quantitative and qualitative approaches through the pragmatic worldview to achieve the main purpose of the study. Adopting a survey study design, data was collected from five selected Ghanaian public universities by interviewing the five university librarians/directors, using questionnaires on 313 library staff and making observations within the five libraries. The findings of the study established that the managerial tools/instruments required for effective ICTs management in Ghanaian university libraries include the availability of library ICT policies, a library ICT strategic plan, library ICT installation and maintenance manuals, library ICT integration plans, and standard operations manuals. In addition, adequate funds, skilled manpower, adequate and standard ICT infrastructures among others. However, the study also revealed that there are absence of library ICT policies, lack of processes and procedure guidelines, inadequate funds, lack of management support, inadequate ICT skills among libraries and staff ICT training policies in the academic libraries in Ghana. The study recommends the formulation of ICT policies and strategic plans purposely for the comprehensive management of library ICT systems. Furthermore, the university top management should support their libraries by providing the required resources and motivation for the library managers including the development of stakeholder partnership and collaboration. To galvanise these recommendations, the study proposes a framework for the ICTs adoption and management in Ghanaian university libraries. / Information Science / D. Litt. et Phil. (Information Science)