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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
1

A study of urinary-type plasminogen activators in biological fluids

張濤, Cheung, To. January 1996 (has links)
published_or_final_version / Biochemistry / Doctoral / Doctor of Philosophy
2

Modulation of plasminogen activator and plasminogen activator inhibitor system in murine macrophage /

Kung, Kam-pun. January 1900 (has links)
Thesis (M. Phil.)--University of Hong Kong, 1992.
3

A study of urinary-type plasminogen activators in biological fluids /

Cheung, To. January 1996 (has links)
Thesis (Ph. D.)--University of Hong Kong, 1996. / Includes bibliographical references (leaf 166-197).
4

Transcription activation and DNA binding by the MelR protein

Howard, Victoria Jayne January 2001 (has links)
No description available.
5

Factors affecting plasminogen activator activity in bovine and porcine oocyte-cumulus cell complexes matured in vitro

Kim, Nam-hyung 06 May 1993 (has links)
Effects of phorbol myristate acetate (PMA), dibutyryl cyclic AMP (dbcAMP), 6-dimethylaminopurine (6-DMAP), okadaic acid (OA), cycloheximide (CHX), actinomycin D (AcD) and tunicamycin (TuM) on plasminogen activator (PA) activity and maturation rate in bovine and porcine oocyte-cumulus cell complexes (BOCC and POCC, respectively) in vitro were determined. Plasminogen activator activity was measured by SDS-PAGE, casein-agar zymography and densitometry. Three plasmingen-dependent lytic zones (92-95, 71-73 and 49-51 kD) and one PA inhibitor (52 kD) were observed in BOCC. Immunoprecipitation and amiloride sensitivity suggested that the 49-51 kD protease is a urokinase type PA (uPA), the 71-73 and 92-95 kD proteases are a tissue type PA (tPA) and tPA-PAI complex, respectively, and the PAI is PAI-1. In POCC, two plasminogen activators (71-78 and 93-96 KD) were observed. Lack of amiloride sensitivity suggested that the 71 -78 kD band is a tPA and the 93-96 kD band is possibly a tPA-PAI complex. Increasing dbcAMP in the culture medium increased activity in both BOCC and POCC in dose-dependent fashion (P<0.05). In BOCC cultured with PMA, total PA activity increased, however high concentrations of PMA (10 and 100 ng/ml) decreased tPA activity in matured POCC. Plasminogen activator activity decreased in 6-DMAP, actinomycin D and cycloheximide and oocyte maturation was also inhibited in these treatments. When POCC were treated with 25 nM OA, uPA activity was observed. Plasminogen activator activity increased in either BOCC or POCC treated with up to 25 nM OA, however PA activity decreased at concentrations greater than 75 nM (P<0.05). Incubation of BOCC with tunicamycin reduced the molecular mass of tPA and tPA-PAI complex and PAI-1 by 5-10%, however PA activity was not inhibited. These data suggest that BOCC matured in vitro produce uPA, tPA and PAI-1 however POCC produce only tPA and PAI. The production of PA and PAI by either BOCC or POCC is associated with oocyte maturation and influenced by stimulators of the protein kinase A and C, modulators of intracellular phosphorylation and metabolic inhibitors. / Graduation date: 1993
6

Modulation of plasminogen activator and plasminogen activator inhibitor system in murine macrophage

龔金斌, Kung, Kam-pun. January 1992 (has links)
published_or_final_version / Biochemistry / Master / Master of Philosophy
7

Sonic hedgehog in the vertebrate retina /

Moshiri, Ala. January 2004 (has links)
Thesis (Ph. D.)--University of Washington, 2004. / Vita. Includes bibliographical references (leaves 99-108).
8

The regulation and function of plasminogen activator inhibitor type 2 /

Dickinson, Joanne L. January 1995 (has links) (PDF)
Thesis (Ph.D.) - University of Queensland, 1996. / Includes bibliographical references.
9

Study of plasminogen activation by human trophoblasts /

Jojart, Istvan, January 1997 (has links)
Thesis (Ph.D.)--Memorial University of Newfoundland, Faculty of Medicine, 1997. / Typescript. Bibliography: leaves [222]-256.
10

Post-transcriptional regulation of plasminogen activator inhibitor type 2

Tierney, Marcus John, 1973- January 2002 (has links)
Abstract not available

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